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Western Blot (WB) (Western Blot analysis Representative lot data: HeLa lysate was probed with Anti-Kindlin-2, clone 3A3 (0.5ug/mL). Protein was visualized using a Goat anti-Mouse IgG secondary antibody conjugated to HRP and detected using a chemiluminescence detection system Arrow indicates Kindlin-2 (~ 70 kDa).)

Mouse anti-Human Kindlin-2 Monoclonal Antibody | anti-KIND2 antibody

Kindlin-2 (Fermitin family homolog 2, KIND2, Kindlin-2, MIG2, mig-2, MIG-2, Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin homology domain-containing family C member 1, PLEKHC1, UNC112, UNC112B, FERMT2) (HRP)

Gene Names
FERMT2; MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B
Reactivity
Human
Applications
Immunocytochemistry, Western Blot
Purity
Purified by Ammonium Sulfate Precipitation
Synonyms
Kindlin-2; Monoclonal Antibody; Kindlin-2 (Fermitin family homolog 2; KIND2; MIG2; mig-2; MIG-2; Mitogen-inducible gene 2 protein; PH domain-containing family C member 1; Pleckstrin homology domain-containing family C member 1; PLEKHC1; UNC112; UNC112B; FERMT2) (HRP); anti-KIND2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
10H13
Specificity
Recognizes human Kindlin-2. Species sequence homology: mouse, rat, bovine.
Purity/Purification
Purified by Ammonium Sulfate Precipitation
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Applicable Applications for anti-KIND2 antibody
Immunocytochemistry (ICC), Western Blot (WB)
Immunogen
Recombinant protein corresponding to human Kindlin-2 (GST-tagged).
Conjugate
HRP
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western Blot analysis Representative lot data: HeLa lysate was probed with Anti-Kindlin-2, clone 3A3 (0.5ug/mL). Protein was visualized using a Goat anti-Mouse IgG secondary antibody conjugated to HRP and detected using a chemiluminescence detection system Arrow indicates Kindlin-2 (~ 70 kDa).)

Western Blot (WB) (Western Blot analysis Representative lot data: HeLa lysate was probed with Anti-Kindlin-2, clone 3A3 (0.5ug/mL). Protein was visualized using a Goat anti-Mouse IgG secondary antibody conjugated to HRP and detected using a chemiluminescence detection system Arrow indicates Kindlin-2 (~ 70 kDa).)
Product Categories/Family for anti-KIND2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,675 Da
NCBI Official Full Name
fermitin family homolog 2 isoform 2
NCBI Official Synonym Full Names
fermitin family member 2
NCBI Official Symbol
FERMT2
NCBI Official Synonym Symbols
MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B
NCBI Protein Information
fermitin family homolog 2; PH domain-containing family C member 1; kindlin 2; kindlin-2; mitogen inducible gene 2 protein; mitogen-inducible gene 2 protein; pleckstrin homology domain containing, family C (with FERM domain) member 1; pleckstrin homology d
UniProt Protein Name
Fermitin family homolog 2
UniProt Gene Name
FERMT2
UniProt Synonym Gene Names
KIND2; MIG2; PLEKHC1; MIG-2; PH domain-containing family C member 1

Uniprot Description

Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.

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Product Notes

The KIND2 fermt2 (Catalog #AAA6244092) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Kindlin-2 (Fermitin family homolog 2, KIND2, Kindlin-2, MIG2, mig-2, MIG-2, Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin homology domain-containing family C member 1, PLEKHC1, UNC112, UNC112B, FERMT2) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kindlin-2 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the KIND2 fermt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kindlin-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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