Immunohistochemistry (IHC)
(Fig.1. IHC-P staining of mouse kidney tissue, diluted at 1:200.)
Mouse Kif 7 Monoclonal Antibody | anti-Kif 7 antibody
Kif 7 Monoclonal Antibody
Gene Names
KIF7; ACLS; AGBK; HLS2; JBTS12; UNQ340
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence
Purity
Affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Synonyms
Kif 7; Monoclonal Antibody; Kif 7 Monoclonal Antibody; Mouse Anti-Kif 7 Monoclonal Antibody; anti-Kif 7 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Specificity
The antibody detects endogenous Kif 7 proteins.
Purity/Purification
Affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Form/Format
Liquid; PBS, pH 7.4, Containing 0.02% Sodium Azide As Preservative and 50% Glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1343
Applicable Applications for anti-Kif 7 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
Application Notes
IF: 1:100-1:200
IHC-P: 1:200
IHC-P: 1:200
Immunogen
Synthetic Peptide
Preparation and Storage
Stable for one year at -20 degree C from date of shipment.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Fig.1. IHC-P staining of mouse kidney tissue, diluted at 1:200.)
Immunohistochemistry (IHC)
(Fig.1. IHC-P staining of mouse kidney tissue, diluted at 1:200.)
Immunofluorescence (IF)
(Fig.2. Immunofluorescence analysis of mouse colon tissue. 1, Kif 7 Monoclonal Antibody (red) was diluted at 1:200 (4 degree C, overnight). 2, Cy3 Labeled secondary antibody was diluted at 1:300 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min. Picture A: Target. Picture B: DAPI. Picture C: merge of A+B.)
Immunofluorescence (IF)
(Fig.2. Immunofluorescence analysis of mouse colon tissue. 1, Kif 7 Monoclonal Antibody (red) was diluted at 1:200 (4 degree C, overnight). 2, Cy3 Labeled secondary antibody was diluted at 1:300 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min. Picture A: Target. Picture B: DAPI. Picture C: merge of A+B.)
Related Product Information for anti-Kif 7 antibody
KIF7 encodes a cilia-associated protein (kinesin family member 7) belonging to the kinesin family. Kinesin family member 7 plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in KIF7 have been associated with various ciliopathies.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
kinesin-like protein KIF7
NCBI Official Synonym Full Names
kinesin family member 7
NCBI Official Symbol
KIF7
NCBI Official Synonym Symbols
ACLS; AGBK; HLS2; JBTS12; UNQ340
NCBI Protein Information
kinesin-like protein KIF7
UniProt Protein Name
Kinesin-like protein KIF7
UniProt Gene Name
KIF7
UniProt Entry Name
KIF7_HUMAN
NCBI Description
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]
Research Articles on Kif 7
Similar Products
Product Notes
The Kif 7 kif7 (Catalog #AAA9700362) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Kif 7 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kif 7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF). IF: 1:100-1:200 IHC-P: 1:200. Researchers should empirically determine the suitability of the Kif 7 kif7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kif 7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
