Testing Data
(Detection limit for recombinant GST tagged KCNMB4 is ~0.3ng/ml as a capture antibody.)
Mouse anti-Human KCNMB4 Monoclonal Antibody | anti-KCNMB4 antibody
KCNMB4 (Calcium-activated Potassium Channel Subunit beta-4, BK Channel Subunit beta-4, BKbeta4, Hbeta4, Calcium-activated Potassium Channel, Subfamily M Subunit beta-4, Charybdotoxin Receptor Subunit beta-4, K(VCA)beta-4, Maxi K Channel Subunit beta-4, Sl
Reactivity
Human
Applications
ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KCNMB4; Monoclonal Antibody; KCNMB4 (Calcium-activated Potassium Channel Subunit beta-4; BK Channel Subunit beta-4; BKbeta4; Hbeta4; Calcium-activated Potassium Channel; Subfamily M Subunit beta-4; Charybdotoxin Receptor Subunit beta-4; K(VCA)beta-4; Maxi K Channel Subunit beta-4; Sl; anti-KCNMB4 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1G7
Specificity
Recognizes human KCNMB4.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Sequence Length
1148
Applicable Applications for anti-KCNMB4 antibody
ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length recombinant corresponding to aa1-211 from human KCNMB4 (AAH50621) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS*
Conjugate
FITC
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(Detection limit for recombinant GST tagged KCNMB4 is ~0.3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged KCNMB4 is ~0.3ng/ml as a capture antibody.)
Related Product Information for anti-KCNMB4 antibody
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
Product Categories/Family for anti-KCNMB4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 4, mRNA
NCBI Official Synonym Full Names
potassium calcium-activated channel subfamily M regulatory beta subunit 4
NCBI Official Symbol
KCNMB4
NCBI Protein Information
calcium-activated potassium channel subunit beta-4
Protein Family
NCBI Description
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
Research Articles on KCNMB4
Similar Products
Product Notes
The KCNMB4 (Catalog #AAA6147881) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The KCNMB4 (Calcium-activated Potassium Channel Subunit beta-4, BK Channel Subunit beta-4, BKbeta4, Hbeta4, Calcium-activated Potassium Channel, Subfamily M Subunit beta-4, Charybdotoxin Receptor Subunit beta-4, K(VCA)beta-4, Maxi K Channel Subunit beta-4, Sl reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNMB4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KCNMB4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNMB4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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