Rat anti-Mouse Kallikrein B1 Monoclonal Antibody | anti-Klk1b1 antibody
Kallikrein B1 (KLKB1, Plasma Kallikrein)
Gene Names
Klk1b1; TK; mK1; Klk1; mGK-1
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Kallikrein B1; Monoclonal Antibody; Kallikrein B1 (KLKB1; Plasma Kallikrein); Anti -Kallikrein B1 (KLKB1; anti-Klk1b1 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7H97
Specificity
Recognizes mouse Kallikrein B1.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
Applicable Applications for anti-Klk1b1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1-2ug/ml
ELISA: 0.5-1ug/ml
Dilution: Western Blot: 1-2ug/ml
ELISA: 0.5-1ug/ml
Immunogen
NS0-derived recombinant mouse KLKB1 (aa20-638) Accession # NP_032481
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Klk1b1 antibody
Kallikrein B1 (KLKB1) is a serine protease synthesized in the liver and circulated in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. It plays an important role in blood pressure regulation, fibrinolysis, and neutrophil activation. Mouse KLKB1 precursor contains a signal peptide (residues 1 to 19) and a pro form sequence (residues 20 to 638). Upon activation, the pro form is converted to a heavy chain and a light chain, which is linked by disulfide bonds and the latter contains the catalytic domain. The amino acid sequence of mouse KLKB1 is 90%, 77% and 76% identical to that of rat, canine and human.
Product Categories/Family for anti-Klk1b1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,022 Da
NCBI Official Full Name
kallikrein 1-related peptidase b1
NCBI Official Synonym Full Names
kallikrein 1-related peptidase b1
NCBI Official Symbol
Klk1b1
NCBI Official Synonym Symbols
TK; mK1; Klk1; mGK-1
NCBI Protein Information
kallikrein 1-related peptidase b1; tissue kallikrein; tissue kallikrein-1; glandular kallikrein K1
UniProt Protein Name
Kallikrein 1-related peptidase b1
Protein Family
UniProt Gene Name
Klk1b1
UniProt Synonym Gene Names
Klk-1; Klk1
UniProt Entry Name
K1KB1_MOUSE
Uniprot Description
KLK2: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.35; Protease
Cellular Component: nucleus
Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity
Biological Process: regulation of systemic arterial blood pressure; tissue kallikrein-kinin cascade; proteolysis; vasodilation; cardiac muscle contraction
Research Articles on Klk1b1
Similar Products
Product Notes
The Klk1b1 klk1b1 (Catalog #AAA601164) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Kallikrein B1 (KLKB1, Plasma Kallikrein) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Kallikrein B1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Dilution: Western Blot: 1-2ug/ml ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the Klk1b1 klk1b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kallikrein B1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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