ICC (Immunocytochemistry)
(ICC staining ZO2 in A431 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit anti-Human, Mouse ZO2 Polyclonal Antibody | anti-ZO2 antibody
ZO2 Antibody
Gene Names
TJP2; ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot
Purity
Peptide affinity purified
Synonyms
ZO2, Antibody; ZO2 Antibody; C9DUPq21.11 antibody; DFNA51 antibody; DUP9q21.11 antibody; Friedreich ataxia region gene X104 (tight junction protein ZO-2) antibody; MGC26306 antibody; PFIC4 antibody; Tight junction protein 2 antibody; Tight junction protein ZO 2 antibody; Tight junction protein ZO-2 antibody; TJP2 antibody; X104 antibody; ZO 2 antibody; ZO-2 antibody; ZO2 antibody; ZO2_HUMAN antibody; Zona occludens 2 antibody; Zona occludens protein 2 antibody; Zonula occludens protein 2 antibody; anti-ZO2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Peptide affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-ZO2 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
Peptide
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining ZO2 in A431 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining ZO2 in A431 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
WB (Western Blot)
(Western blot analysis on cell lysates using anti-ZO2 rabbit polyclonal antibodies.)
WB (Western Blot)
(Western blot analysis on cell lysates using anti-ZO2 rabbit polyclonal antibodies.)
Related Product Information for anti-ZO2 antibody
Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane proteins between the apical and the basolateral cell surfaces. Zona occludens proteins ZO-1, -2, and -3 (also known as TJP1, 2, and 3) are peripheral membrane adaptor proteins that link junctional transmembrane proteins such as occludin and claudin to the actin cytoskeleton. ZO-1 and -2 are required for tight junction formation and function. In subconfluent proliferating cells, ZO-1 and ZO-2 have been shown to colocalize to the nucleus and play a role in transcriptional regulation, possibly through facilitating nuclear import/export of transcriptional regulators.
Product Categories/Family for anti-ZO2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
133,958 Da
NCBI Official Full Name
tight junction protein ZO-2 isoform 1
NCBI Official Synonym Full Names
tight junction protein 2
NCBI Official Symbol
TJP2
NCBI Official Synonym Symbols
ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11
NCBI Protein Information
tight junction protein ZO-2; zona occludens 2; zonula occludens protein 2; Friedreich ataxia region gene X104 (tight junction protein ZO-2)
UniProt Protein Name
Tight junction protein ZO-2
UniProt Gene Name
TJP2
UniProt Synonym Gene Names
X104; ZO2
UniProt Entry Name
ZO2_HUMAN
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Product Notes
The ZO2 tjp2 (Catalog #AAA311945) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZO2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZO2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ZO2 tjp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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