Testing Data
(Huvec (non-reducing) cell lysate was probed withMBS600125, Integrin alpha1 (1:1000 dilution). Proteins were visualized using a goat anti-mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates target (~110kD))
Mouse anti-Human Integrin alpha1 I Monoclonal Antibody | anti-ITGA1 antibody
Integrin alpha1 I (MaxLight 490)
Testing Data
(Huvec (non-reducing) cell lysate was probed withMBS600125, Integrin alpha1 (1:1000 dilution). Proteins were visualized using a goat anti-mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates target (~110kD))
Testing Data
(Huvec (non-reducing) cell lysate was probed withMBS600125, Integrin alpha1 (1:1000 dilution). Proteins were visualized using a goat anti-mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates target (~110kD))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]
Uniprot Description
ITGA1: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Belongs to the integrin alpha chain family.
Protein type: Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: neuron projection; focal adhesion; cell surface; membrane; plasma membrane; acrosome; perikaryon; integrin complex; lipid raft; external side of plasma membrane
Molecular Function: collagen binding; protein binding; metal ion binding; protein phosphatase binding; receptor binding
Biological Process: positive regulation of phosphoprotein phosphatase activity; integrin-mediated signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; axon guidance; neutrophil chemotaxis; extracellular matrix organization and biogenesis; activation of MAPK activity; cell-matrix adhesion; vasodilation; negative regulation of cell proliferation; muscle contraction; cellular extravasation; positive regulation of neuron apoptosis; blood coagulation
Research Articles on ITGA1
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Product Notes
The ITGA1 itga1 (Catalog #AAA6245436) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Integrin alpha1 I (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alpha1 I can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the ITGA1 itga1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alpha1 I, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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