Integrin alpha 4 Recombinant Antibody | ITGA4 recombinant antibody
Anti-Integrin alpha 4 [Natalizumab]
Gene Names
itga4.S; itga4
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
PurifiedProtein A Affinity Purified
Synonyms
Integrin alpha 4; Monoclonal Recombinant Antibody; Anti-Integrin alpha 4 [Natalizumab]; CD49D; alpha 4 subunit of VLA-4 receptor; Integrin alpha-IV; ITGA4 recombinant antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
Human IgG4, kappa
Clone Number
Natalizumab
Specificity
This antibody binds to the alpha 4 binds subunit of alpha4beta1 (also known as very lateantigen 4 [VLA-4] or CD49d-CD29) and alpha4beta7 integrin
Purity/Purification
Purified
Protein A Affinity Purified
Protein A Affinity Purified
Sequence Length
1032
Applicable Applications for ITGA4 recombinant antibody
Block, Flow Cytometry (FC/FACS)
Immunogen
The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Antigen
Integrin alpha 4
Antigen Description
The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Buffer Composition
PBS only with 0.02% Proclin 300.
Chimeric Use Statement
This is a research-grade biosimilar.
Publication Note
Describes the safety and pharmacokinetic characterization of this antibody in a clinical setting.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for ITGA4 recombinant antibody
Recombinant monoclonal antibody to Integrin alpha 4. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibodyNatalizumab.
Product Categories/Family for ITGA4 recombinant antibody
References
Sheremata et al. Neurology. 1999 Mar 23;52(5):1072-4. PMID:10102433
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
115,215 Da
NCBI Official Full Name
integrin alpha 4
NCBI Official Synonym Full Names
integrin subunit alpha 4 S homeolog
NCBI Official Symbol
itga4.S
NCBI Official Synonym Symbols
itga4
NCBI Protein Information
integrin alpha-4
UniProt Protein Name
Integrin alpha-4
Protein Family
UniProt Gene Name
itga4
Uniprot Description
Fibronectin and V-CAM adhesion receptor.
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Product Notes
The ITGA4 itga4 (Catalog #AAA488267) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Integrin alpha 4 [Natalizumab] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alpha 4 can be used in a range of immunoassay formats including, but not limited to, Block, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the ITGA4 itga4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alpha 4, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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