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Western Blot (Sample: Recombinant INHA, Human.)

Mouse Inhibin A Monoclonal Antibody | anti-INHA antibody

Inhibin A (INHA) Monoclonal Antibody

Reactivity
Homo sapiens (Human)
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Protein A + Protein G affinity chromatography
Synonyms
Inhibin A; Monoclonal Antibody; Inhibin A (INHA) Monoclonal Antibody; INH-A; anti-INHA antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Homo sapiens (Human)
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
C2
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid; Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-INHA antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes
Western blotting: 0.5-5ug/mL
Immunohistochemistry: 5-50ug/mL
Immunocytochemistry: 5-50ug/mL
Optimal working dilutions must be determined by end user.
Source
Monoclonal antibody preparation
Cross Reactivity
Rat
Immunogen
Synthetic Peptide, INHa conjugated to KLH.
Target peptide sequence: RTTSDGGYSFKYETVPNLLTQ (MBS2086137 ).
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot

(Sample: Recombinant INHA, Human.)

Western Blot (Sample: Recombinant INHA, Human.)

Western Blot (WB)

(Western Blot;Sample: Rat Cerebrum lysate;Primary Ab: 5ug/ml Mouse Anti-Human INHA AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))

Western Blot (WB) (Western Blot;Sample: Rat Cerebrum lysate;Primary Ab: 5ug/ml Mouse Anti-Human INHA AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
inhibin alpha chain preproprotein
NCBI Official Synonym Full Names
inhibin alpha subunit
NCBI Official Symbol
INHA
NCBI Protein Information
inhibin alpha chain
UniProt Protein Name
Inhibin alpha chain
Protein Family
UniProt Gene Name
INHA

NCBI Description

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]

Uniprot Description

INHA: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cell soma; cytoplasm; extracellular region; photoreceptor inner segment; photoreceptor outer segment

Molecular Function: cytokine activity; growth factor activity; hormone activity; protein binding; protein heterodimerization activity; receptor binding; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cell cycle arrest; cell development; cell differentiation; cell surface receptor signaling pathway; cell-cell signaling; erythrocyte differentiation; hemoglobin biosynthetic process; male gonad development; negative regulation of B cell differentiation; negative regulation of cell cycle; negative regulation of follicle-stimulating hormone secretion; negative regulation of interferon-gamma biosynthetic process; negative regulation of macrophage differentiation; negative regulation of phosphorylation; nervous system development; ovarian follicle development; positive regulation of follicle-stimulating hormone secretion; regulation of apoptosis; regulation of cell cycle; regulation of cell proliferation; regulation of MAPK cascade; response to external stimulus; signal transduction; skeletal system development

Research Articles on INHA

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Product Notes

The INHA inha (Catalog #AAA2032024) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Inhibin A (INHA) Monoclonal Antibody reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Inhibin A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-5ug/mL Immunohistochemistry: 5-50ug/mL Immunocytochemistry: 5-50ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the INHA inha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Inhibin A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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