ELISA (EIA)
(Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human IL2RA, His tagged protein can bind Anti-IL2RA Neutralizing antibody in a linear range of 0.64-400 ng/ml.)
Chimeric anti-Human IL2RA Monoclonal Antibody | anti-IL2RA antibody
Anti-IL2RA (basiliximab biosimilar) mAb
FC/FACS: 1:100
Estimated 12 months from date of dispatch
ELISA (EIA)
(Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human IL2RA, His tagged protein can bind Anti-IL2RA Neutralizing antibody in a linear range of 0.64-400 ng/ml.)
ELISA (EIA)
(Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human IL2RA, His tagged protein can bind Anti-IL2RA Neutralizing antibody in a linear range of 0.64-400 ng/ml.)
Testing Data
(Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human IL2RA (A) were surface stained with Anti-IL2RA mAb 1 ug/ml (basiliximab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.)
Testing Data
(Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human IL2RA (A) were surface stained with Anti-IL2RA mAb 1 ug/ml (basiliximab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.)
NCBI and Uniprot Product Information
NCBI Description
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Uniprot Description
IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 10p15-p14
Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: interleukin-2 receptor activity; drug binding; interleukin-2 binding
Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; apoptosis; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; cell proliferation; negative regulation of T cell proliferation; inflammatory response to antigenic stimulus; cell surface receptor linked signal transduction; positive regulation of T cell differentiation; negative regulation of inflammatory response; immune response; inflammatory response; activated T cell apoptosis
Disease: Interleukin 2 Receptor, Alpha, Deficiency Of; Diabetes Mellitus, Insulin-dependent, 10
Research Articles on IL2RA
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Product Notes
The IL2RA il2ra (Catalog #AAA188610) is an Antibody produced from Chimeric and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL2RA (basiliximab biosimilar) mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL2RA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS). ELISA: 1:5000-10,000 FC/FACS: 1:100. Researchers should empirically determine the suitability of the IL2RA il2ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL2RA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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