Western Blot (WB)
(Western Blot analysis of IL22RA1 expression in transfected 293T cell line by IL22RA1 monoclonal antibody.|Lane 1: IL22RA1 transfected lysate (63.1kD).|Lane 2: Non-transfected lysate.)
Mouse anti-Human IL22RA1 Monoclonal Antibody | anti-IL22RA1 antibody
IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
IL22RA1; Monoclonal Antibody; IL22RA1 (Interleukin-22 Receptor Subunit alpha-1; IL-22 Receptor Subunit alpha-1; IL-22R-alpha-1; IL-22RA1; Cytokine Receptor Class-II Member 9; Cytokine Receptor Family 2 Member 9; CRF2-9; ZcytoR11; IL22R); Anti -IL22RA1 (Interleukin-22 Receptor Subunit alpha-1; anti-IL22RA1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3,k
Clone Number
6B5
Specificity
Recognizes human IL22RA1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
EDPSDLLQHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLTVETGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLELQVNRTYQMHLGGKQREYEFFGLTPDTEFLGTIMICVPTWAKESAPYMCRVKTLPDRTWTYSFSGAFLFSMGFLVAVLCYLSYRYVTKPPAPPNSLNVQRVLTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQILSPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSYGVCMEGSGKDSPTGTLSSPKHLRPKGQLQKEPPAGSCMLGGLSLQEVTSLAMEESQEAKSLHQPLGICTDRTSDPNVLHSGEEGTPQYLKGQLPLLSSVQIEGHPMSLPLQPPSRPCSPSDQGPSPWGLLESLVCPKDEAKSPAPETSDLEQPTELDSLFRGLALTVQWES
Applicable Applications for anti-IL22RA1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Immunogen
Full length recombinant corresponding to aa19-575 from human IL22RA1 (AAH29273) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of IL22RA1 expression in transfected 293T cell line by IL22RA1 monoclonal antibody.|Lane 1: IL22RA1 transfected lysate (63.1kD).|Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of IL22RA1 expression in transfected 293T cell line by IL22RA1 monoclonal antibody.|Lane 1: IL22RA1 transfected lysate (63.1kD).|Lane 2: Non-transfected lysate.)
Testing Data
(Detection limit for recombinant GST tagged IL22RA1 is ~1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged IL22RA1 is ~1ng/ml as a capture antibody.)
Related Product Information for anti-IL22RA1 antibody
The interleukin-22 receptor A1 (IL-22 Ra1), also known as CRF2-9, is a 557aa, ~65kD type I transmembrane protein of the type II cytokine receptor family (CRF). IL-22 RA1 forms an IL-22 signaling complex with IL-10 RB/CRF2-4 on epithelial and stromal cells. IL-22 engagement of the signaling complex stimulates antimicrobial, acute phase and proinflammatory protein expression. IL-22 Ra1 also pairs with IL-20 RB to form a receptor that is responsive to IL-20 and IL-24. Within the 211aa extracellular domain, mouse IL-22 Ra1 shares 78% and 94% aa sequence identity with human and rat IL-22 RA1.
Product Categories/Family for anti-IL22RA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,776 Da
NCBI Official Full Name
interleukin-22 receptor subunit alpha-1
NCBI Official Synonym Full Names
interleukin 22 receptor, alpha 1<
NCBI Official Symbol
IL22RA1
NCBI Protein Information
interleukin-22 receptor subunit alpha-1; IL-22RA1; IL-22R-alpha-1; IL-22 receptor subunit alpha-1
UniProt Protein Name
Interleukin-22 receptor subunit alpha-1
Protein Family
UniProt Gene Name
IL22RA1
UniProt Synonym Gene Names
IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1
UniProt Entry Name
I22R1_BOVIN
Uniprot Description
Function: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation
By similarity.
Subunit structure: Heterodimer with IL10RB and with IL20RB
By similarity.
Subcellular location: Membrane; Single-pass type I membrane protein.
Sequence similarities: Belongs to the type II cytokine receptor family.Contains 2 fibronectin type-III domains.
Research Articles on IL22RA1
Similar Products
Product Notes
The IL22RA1 il22ra1 (Catalog #AAA6011871) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL22RA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the IL22RA1 il22ra1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EDPSDLLQHV KFQSSNFENI LTWDSGPEGT PDTVYSIEYK TYGERDWVAK KGCQRITRKS CNLTVETGNL TELYYARVTA VSAGGRSATK MTDRFSSLQH TTLKPPDVTC ISKVRSIQMI VHPTPTPIRA GDGHRLTLED IFHDLFYHLE LQVNRTYQMH LGGKQREYEF FGLTPDTEFL GTIMICVPTW AKESAPYMCR VKTLPDRTWT YSFSGAFLFS MGFLVAVLCY LSYRYVTKPP APPNSLNVQR VLTFQPLRFI QEHVLIPVFD LSGPSSLAQP VQYSQIRVSG PREPAGAPQR HSLSEITYLG QPDISILQPS NVPPPQILSP LSYAPNAAPE VGPPSYAPQV TPEAQFPFYA PQAISKVQPS SYAPQATPDS WPPSYGVCME GSGKDSPTGT LSSPKHLRPK GQLQKEPPAG SCMLGGLSLQ EVTSLAMEES QEAKSLHQPL GICTDRTSDP NVLHSGEEGT PQYLKGQLPL LSSVQIEGHP MSLPLQPPSR PCSPSDQGPS PWGLLESLVC PKDEAKSPAP ETSDLEQPTE LDSLFRGLAL TVQWES. It is sometimes possible for the material contained within the vial of "IL22RA1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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