Mouse anti-Human IL-17F Monoclonal Antibody | anti-IL-17F antibody
Mouse Anti-Human IL-17F Detection Antibody, Biotin Conjugated Clone B-F60
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.
Subunit structure: Homodimer; disulfide-linked. Ref.7
Subcellular location: Secreted.
Tissue specificity: Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
Involvement in disease: Familial candidiasis 6 (CANDF6) [MIM:613956]: A primary immunodeficiency disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.8
Sequence similarities: Belongs to the IL-17 family.
Sequence caution: The sequence AAL14427.1 differs from that shown. Reason: Intron retention.The sequence CAD92646.1 differs from that shown. Reason: Erroneous gene model prediction.
Research Articles on IL-17F
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Product Notes
The IL-17F il17f (Catalog #AAA335326) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human IL-17F Detection Antibody, Biotin Conjugated Clone B-F60 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-17F can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), ELISpot (ES). ELISA Detection Antibody. This Antibody can be used as Detection in a human IL-17F sandwich Immunoassay to detect human IL-17F in combination with human IL-17F Capture Antibody (Cat n degree879.980.001). The suggested coating concentration range below should be optimised by each laboratory for each application. Researchers should empirically determine the suitability of the IL-17F il17f for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-17F, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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