Testing Data
(Figure-1: Intracellular staining of IL-17A in PBMC treated with PMA (25ng/ml) and ionomycin (250ng/ml) for overnight, then Brefedin A (1x) was added to cells for 4hr prior to harvest. Anti- IL-17A (Clone: ABM2B14) was used at 2 ug/10^6 cells. Green represents isotype control; red represents Anti-IL-17A. Goat anti-mouse PE conjugate was used as secondary antibody.)
Mouse anti-Human IL-17A Monoclonal Antibody | anti-IL-17A antibody
Monoclonal Antibody to IL-17A (Clone: ABM2B14)
Protein G Chromatography
Protein G Chromatography
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
Testing Data
(Figure-1: Intracellular staining of IL-17A in PBMC treated with PMA (25ng/ml) and ionomycin (250ng/ml) for overnight, then Brefedin A (1x) was added to cells for 4hr prior to harvest. Anti- IL-17A (Clone: ABM2B14) was used at 2 ug/10^6 cells. Green represents isotype control; red represents Anti-IL-17A. Goat anti-mouse PE conjugate was used as secondary antibody.)
Testing Data
(Figure-1: Intracellular staining of IL-17A in PBMC treated with PMA (25ng/ml) and ionomycin (250ng/ml) for overnight, then Brefedin A (1x) was added to cells for 4hr prior to harvest. Anti- IL-17A (Clone: ABM2B14) was used at 2 ug/10^6 cells. Green represents isotype control; red represents Anti-IL-17A. Goat anti-mouse PE conjugate was used as secondary antibody.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Uniprot Description
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
Research Articles on IL-17A
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Product Notes
The IL-17A il17a (Catalog #AAA668973) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to IL-17A (Clone: ABM2B14) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-17A can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FC/FACS: 2-4 ug/cells10^6 . Researchers should empirically determine the suitability of the IL-17A il17a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-17A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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