Mouse IL-16 Monoclonal Antibody | anti-IL-16 antibody
mAb anti-Human IL-16
mAb 323 exhibits no detectable cross-reaction with human serum albumin, bovine serum albumin and other human cytokines or growth factors tested, such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF
mAb 323 exhibits no detectable cross-reaction with human serum albumin, bovine serum albumin and other human cytokines or growth factors tested, such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Uniprot Description
IL16: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. 3 isoforms of the human protein are produced by alternative promoter.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Cytokine
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: extracellular space; cytoplasm; plasma membrane; nucleus
Molecular Function: cytokine activity
Biological Process: viral reproduction; transcription, DNA-dependent; regulation of transcription, DNA-dependent; leukocyte chemotaxis; immune response; induction of positive chemotaxis
Research Articles on IL-16
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Product Notes
The IL-16 il16 (Catalog #AAA592274) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human IL-16 reacts with Human. Other species not tested mAb 323 exhibits no detectable cross-reaction with human serum albumin, bovine serum albumin and other human cytokines or growth factors tested, such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF and may cross-react with other species as described in the data sheet. AAA Biotech's IL-16 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: The antibody matches with capture antibody clone 398 in sandwich ELISA. Researchers should empirically determine the suitability of the IL-16 il16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-16, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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