CHO cells anti-Human Humax-IL8 Monoclonal Antibody
Humax-IL8
Reactivity
Human
Purity
>95%
Synonyms
Humax-IL8; Monoclonal Antibody; BMS-986253; HuMax-IL8; HuMax-Inflam/MDX018; IL-8 (Granulocyte chemotactic protein 1; Monocyte-derived neutrophil-activating peptide; IL-8 (1-77) ; IL-8 (9-77) ; Monocyte-derived neutrophil chemotactic factor; IL-8 (7-77) ; (Ser-IL-8) 72; GCP/IL-8 protein V; MONAP; C-X-C motif chemokine 8; GCP/IL-8 protein I; Neutrophil-ac) [Homo sapiens]; anti-Humax-IL8 antibody
Host
CHO cells
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Purity/Purification
>95%
Form/Format
Liquid. Supplied as solution form in PBS pH 7.4.
Concentration
1mg/ml (varies by lot)
Source
Human
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -80 degree C
Related Product Information for anti-Humax-IL8 antibody
HuMax-IL8 (BMS-986253) is a novel fully human monoclonal antibody that binds to and inhibits IL-8, a chemokine that promotes immune escape and tumor progression.
Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8 (6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8 (5-77) has increased activity on neutrophil activation and IL-8 (7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8 (1-77) , respectively.
Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8 (6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8 (5-77) has increased activity on neutrophil activation and IL-8 (7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8 (1-77) , respectively.
Product Categories/Family for anti-Humax-IL8 antibody
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Product Notes
The Humax-IL8 (Catalog #AAA156712) is an Antibody produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. The Humax-IL8 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Humax-IL8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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