Mouse HP CagA Monoclonal Antibody | anti-HP CagA antibody
mAb anti-HP CagA
Reactivity
HumanCross-reaction with other proteins has not been identified.
Applications
ELISA
Purity
Protein G affinity purified
Synonyms
HP CagA; Monoclonal Antibody; mAb anti-HP CagA; H. pylori (HP) cytotoxin associated gene A protein (CagA); Mouse monoclonal antibody (mAb) against the H. pylori cytotoxin associated gene A protein (CagA); anti-HP CagA antibody
Host
Mouse
Reactivity
Human
Cross-reaction with other proteins has not been identified.
Cross-reaction with other proteins has not been identified.
Clonality
Monoclonal
Isotype
IgG1,Kappa
Clone Number
3C10
Specificity
The mAb reacts with H. pylori CagA.
H. pylori (HP) cytotoxin associated gene A protein (CagA)
H. pylori (HP) cytotoxin associated gene A protein (CagA)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.0
Applicable Applications for anti-HP CagA antibody
ELISA (EIA)
Application Notes
ELISA: HRP conjugated 3C10 selectively detects cell lysate of a CagA containing H. pylori strain in sandwich ELISA assay when clone 10E9 is used as coating antibody. In addition, HRP conjugated clone 3C10 can detect the recombinant CagA antigen in sandwich ELISA if use anti-CagA clone 10E9 or clone 5H10 coated ELISA wells.
Immunogen
A highly immunogenic 32kD CagA fragment, recombinant
Fusion Myeloma
Sp2/0-Ag14
Reconstitution
Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
Research Area
Bacteriology
Product Type
Primary antibody, detection antibody in matched antibody pair.
Target Protein
H. pylori cytotoxin associated gene A (CagA) protein
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-HP CagA antibody
Mouse monoclonal antibody (mAb) to H.pylori cytotoxin associated gene A (CagA) protein.
Background: Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1- 2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains.
Background: Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1- 2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains.
Product Categories/Family for anti-HP CagA antibody
Similar Products
Product Notes
The HP CagA (Catalog #AAA592044) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-HP CagA reacts with Human Cross-reaction with other proteins has not been identified. and may cross-react with other species as described in the data sheet. AAA Biotech's HP CagA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: HRP conjugated 3C10 selectively detects cell lysate of a CagA containing H. pylori strain in sandwich ELISA assay when clone 10E9 is used as coating antibody. In addition, HRP conjugated clone 3C10 can detect the recombinant CagA antigen in sandwich ELISA if use anti-CagA clone 10E9 or clone 5H10 coated ELISA wells. Researchers should empirically determine the suitability of the HP CagA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HP CagA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
