Western Blot (WB)
(HNMT Antibody western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow).)
Mouse anti-Human HNMT Monoclonal Antibody | anti-HNMT antibody
HNMT (HNMT, Histamine N-methyltransferase) (PE)
Western Blot (WB)
(HNMT Antibody western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow).)
Western Blot (WB)
(HNMT Antibody western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
HNMT: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. Belongs to the methyltransferase superfamily. HNMT family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.1.1.8; Amino Acid Metabolism - histidine; Methyltransferase
Chromosomal Location of Human Ortholog: 2q22.1
Cellular Component: nucleoplasm; neuron projection; cytoplasm
Molecular Function: histamine N-methyltransferase activity
Biological Process: methylation; hyperosmotic response; response to tumor cell; response to glucocorticoid stimulus; respiratory gaseous exchange; brain development; response to cocaine; response to amine stimulus
Disease: Asthma, Susceptibility To
Research Articles on HNMT
Similar Products
Product Notes
The HNMT hnmt (Catalog #AAA6257633) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HNMT (HNMT, Histamine N-methyltransferase) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HNMT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the HNMT hnmt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HNMT, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
