SDS-PAGE
(SDS-PAGE Analysis of Purified MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
Rabbit MUC6 (Mucin 6/Gastric Mucin) Monoclonal Antibody | anti-MUC6 antibody
MUC6 (Mucin 6/Gastric Mucin)
Gene Names
MUC6; MUC-6
Reactivity
Human. Others not known.
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
MUC6 (Mucin 6/Gastric Mucin), Antibody; MUC6 (Mucin 6/Gastric Mucin); Gastric mucin 6; MUC6; MUC6 mucin; Mucin 6 oligomeric mucus/gel forming; Mucin glycoprotein Fragment; Mucin-6; Secretory mucin MUC6; anti-MUC6 antibody
Host
Rabbit
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG
Clone Number
MUC6/1553R
Specificity
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
2439
Applicable Applications for anti-MUC6 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence
Cellular Localization
Cytoplasmic and Secreted
Hu-chromosome Location
11p15.5
Positive Control
Stomach
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis of Purified MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
SDS-PAGE
(SDS-PAGE Analysis of Purified MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Pancreas stained with MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Pancreas stained with MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with MUC6 Rabbit Recombinant Monoclonal Antibody (MUC6/1553R).)
References
Reis C A, David L, Correa P, et al. Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression. Cancer Res. 59(5): 1003-1007 (1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
252kDa
NCBI Official Full Name
mucin-6
NCBI Official Synonym Full Names
mucin 6, oligomeric mucus/gel-forming
NCBI Official Symbol
MUC6
NCBI Official Synonym Symbols
MUC-6
NCBI Protein Information
mucin-6
UniProt Protein Name
Mucin-6
UniProt Gene Name
MUC6
UniProt Synonym Gene Names
MUC-6
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Product Notes
The MUC6 muc6 (Catalog #AAA214459) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MUC6 (Mucin 6/Gastric Mucin) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's MUC6 (Mucin 6/Gastric Mucin) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the MUC6 muc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUC6 (Mucin 6/Gastric Mucin), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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