Mouse Helicobacter pylori CagA protein Monoclonal Antibody
Helicobacter pylori CagA protein Monoclonal Antibody
Reactivity
Helicobacter pylori
Applications
ELISA, Immunoblot, Western Blot
Synonyms
Helicobacter pylori CagA protein; Monoclonal Antibody; Helicobacter pylori CagA protein Monoclonal Antibody; anti-Helicobacter pylori CagA protein antibody
Host
Mouse
Reactivity
Helicobacter pylori
Clonality
Monoclonal
Isotype
IgG
Clone Number
HP1811
Specificity
This antibody recognizes an epitope between Asp562 and Gln795 of H. pylori Cag A protein.
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661 fkngknkdfs kaeetlkalk dsvkdlginp ewiskvenln aalnefkngk nkdfskvtqa
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Form/Format
Protein A-purified antibody in PBS, pH7.4, 0.09% sodium azide
Applicable Applications for anti-Helicobacter pylori CagA protein antibody
ELISA (EIA), Immunoblot (IB)
Application Notes
ELISA: Endusers should determine optimal antibody concentrations relative to their preparations of H. pylori.
Antigen
Recombinant fragments of H. pylori CagA protein.
Dilution Instruction
Dilute in PBS or medium that is compatible with the assay system.
Preparation and Storage
Store product at 4 degree C.
Related Product Information for anti-Helicobacter pylori CagA protein antibody
Background: Helicobacter pylori, first associated with peptic ulcer disease, is now also associated with gastric cancer. Investigations by Backert and Blaser of H.pylori genes and antigens identified the 128kDa CagA protein (product of the cagA gene) as a protein associated with an increased risk of gastric cancer. During infection, CagA localizes to the host plasma membrane and undergoes tyrosine phosphorylation. Subsequently, the various forms of CagA interact with >25 host signaling factors promoting proinflammatory, proliferative, cell cycle-related, and antiapoptotic gene alterations. Alterations in cellular growth and of epithelial integrity by CagA can trigger precancerous alterations in the stomach, which is one explanation for the high frequency of gastric cancer in patients carrying CagA+H. pylori.
Product Categories/Family for anti-Helicobacter pylori CagA protein antibody
NCBI and Uniprot Product Information
UniProt Accession #
Similar Products
Product Notes
The Helicobacter pylori CagA protein (Catalog #AAA191589) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Helicobacter pylori CagA protein Monoclonal Antibody reacts with Helicobacter pylori and may cross-react with other species as described in the data sheet. AAA Biotech's Helicobacter pylori CagA protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoblot (IB). ELISA: Endusers should determine optimal antibody concentrations relative to their preparations of H. pylori. Researchers should empirically determine the suitability of the Helicobacter pylori CagA protein for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Helicobacter pylori CagA protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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