Testing Data
Mouse anti-Human Heat Shock 70kD Protein 1-like Monoclonal Antibody | anti-HSPA1L antibody
Heat Shock 70kD Protein 1-like (HSPA1L, hum70t, HSP70-HOM)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: Western Blotting: 1:1000-1:2000
Testing Data
Testing Data
Western Blot (WB)
(Detection of human HSPA1L by Western blot. Samples: Whole cell lysate (50 μg) from HEK293 cells. Predicted molecular weight: 70 kD)
Western Blot (WB)
(Detection of human HSPA1L by Western blot. Samples: Whole cell lysate (50 μg) from HEK293 cells. Predicted molecular weight: 70 kD)
Immunostaining (IS)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with MBS601847 mAb.)
Immunostaining (IS)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with MBS601847 mAb.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq]
Uniprot Description
HSPA1L: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Not induced by heat shock. Expressed in spermatids. Belongs to the heat shock protein 70 family.
Protein type: Chaperone; Heat shock protein; Mitochondrial
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: nucleoplasm; signalosome; mitochondrial matrix; cytosol
Molecular Function: protein binding; unfolded protein binding; ATP binding
Biological Process: binding of sperm to zona pellucida; protein refolding; response to unfolded protein
Research Articles on HSPA1L
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Product Notes
The HSPA1L hspa1l (Catalog #AAA601847) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Heat Shock 70kD Protein 1-like (HSPA1L, hum70t, HSP70-HOM) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Heat Shock 70kD Protein 1-like can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blotting. Dilution: Western Blotting: 1:1000-1:2000. Researchers should empirically determine the suitability of the HSPA1L hspa1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Heat Shock 70kD Protein 1-like, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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