Mouse Heat Labile Enterotoxin Monoclonal Antibody | anti-eltB antibody
Heat Labile Enterotoxin antibody
Applications
ELISA
Purity
> 95% pureHeat Labile Enterotoxin antibody was purified by Protein A or G affinity purification
Synonyms
Heat Labile Enterotoxin; Monoclonal Antibody; Heat Labile Enterotoxin antibody; Monoclonal Heat Labile Enterotoxin; Anti-Heat Labile Enterotoxin; Enterotoxin; anti-eltB antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M120532
Specificity
Reactive to Heat-labile enterotoxin (LT)
Purity/Purification
> 95% pure
Heat Labile Enterotoxin antibody was purified by Protein A or G affinity purification
Heat Labile Enterotoxin antibody was purified by Protein A or G affinity purification
Form/Format
Protein A purified and supplied in PBS, pH 7.4, 3mM KCl, 1.5mM KH2PO4, 140mM NaCl, 8.0mM Na2HPO4 with 0.05% NaN3 as preservative.
Concentration
2.2 mg/ml (varies by lot)
Sequence Length
22
Applicable Applications for anti-eltB antibody
ELISA (EIA)
Application Notes
Use MBS834516 as the capture antibody with MBS834254 as the detection antibody for sandwich immunoassays
Biological Significance
Heat-labile enterotoxin is a type of labile toxin found in Escherichia coli that is inactivated at high temperatures. It acts similarly to the cholera toxin by raising cAMP levels through ADP-ribosylation of the alpha-subunit of a Gs protein leading to the constitutive activation of adenylate cyclase. Elevated cAMP levels stimulate secretion of Chloride ions and water from the enterocyte into the gut lumen, thus causing watery diarrhea. In addition to its effects on chloride secretion, which involve the same steps as the effects of cholera toxin, heat-labile enterotoxin binds additional substrates: lipopolysaccharide on the surface of E Coli cells and A-type blood antigens. The importance of these binding events is not yet known.
Cross-Reactivity
Cross reactive to Cholera toxin (CT)
Biohazard Information
This product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
Heat Labile Enterotoxin antibody was raised in mouse using Heat-labile enterotoxin as the immunogen.
Preparation and Storage
Store at 4 degree C for short term or -20 degree C for longer storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-eltB antibody
Mouse monoclonal Heat Labile Enterotoxin antibody
Product Categories/Family for anti-eltB antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
14,133 Da
NCBI Official Full Name
heat labile enterotoxin, partial
UniProt Protein Name
Heat-labile enterotoxin B chain
UniProt Gene Name
eltB
UniProt Synonym Gene Names
ltpB
UniProt Entry Name
ELBP_ECOLX
Uniprot Description
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
Similar Products
Product Notes
The Heat Labile Enterotoxin eltb (Catalog #AAA834516) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Heat Labile Enterotoxin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Use MBS834516 as the capture antibody with MBS834254 as the detection antibody for sandwich immunoassays. Researchers should empirically determine the suitability of the Heat Labile Enterotoxin eltb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Heat Labile Enterotoxin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
