Mouse GTF2IRD1 Monoclonal Antibody | anti-GTF2IRD1 antibody
GTF2IRD1 (GTF2I Repeat Domain Containing 1, BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1) (AP)
Testing Data
(Detection limit for recombinant GST tagged GTF2IRD1 is 1 ng/ml as a capture antibody.)
Western Blot (WB)
(Western Blot analysis of GTF2IRD1 expression in transfected 293T cell line by GTF2IRD1 monoclonal antibody (M08), clone 2C7.Lane 1: GTF2IRD1 transfected lysate (Predicted MW: 106 KDa).Lane 2: Non-transfected lysate.)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to GTF2IRD1 on HeLa cell. [antibody concentration 10 ug/ml])
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]