Western Blot (WB)
(Western Blot: Sample: Rat Spinal cord lysate; Primary Ab: 3ug/ml Mouse Anti-Human GDF11 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody(Catalog: MBS2086035))
Mouse anti-Human Growth Differentiation Factor 11 Monoclonal Antibody | anti-GDF11 antibody
Growth Differentiation Factor 11 (GDF11) Monoclonal Antibody
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Optimal working dilutions must be determined by end user
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Rat Spinal cord lysate; Primary Ab: 3ug/ml Mouse Anti-Human GDF11 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody(Catalog: MBS2086035))
Western Blot (WB)
(Western Blot: Sample: Rat Spinal cord lysate; Primary Ab: 3ug/ml Mouse Anti-Human GDF11 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody(Catalog: MBS2086035))
Western Blot (WB)
(Western Blot: Sample: Recombinant GDF11, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant GDF11, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Colorectal cancer Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Colorectal cancer Tissue.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]
Uniprot Description
GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: extracellular space; intracellular membrane-bound organelle; nucleoplasm; protein complex
Molecular Function: cytokine activity; growth factor activity; protein binding; transforming growth factor beta receptor binding
Biological Process: camera-type eye morphogenesis; cell development; cell maturation; mesoderm development; metanephros development; negative regulation of cell differentiation; negative regulation of cell proliferation; nervous system development; palate development; pancreas development; regulation of apoptosis; regulation of MAPK cascade; skeletal system development; spinal cord anterior/posterior patterning; ureteric bud development
Research Articles on GDF11
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Product Notes
The GDF11 gdf11 (Catalog #AAA2032017) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Growth Differentiation Factor 11 (GDF11) Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Growth Differentiation Factor 11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western blotting: 0.5-3ug/mL Immunohistochemistry: 5-30ug/mL Immunocytochemistry: 5-30ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the GDF11 gdf11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Growth Differentiation Factor 11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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