Testing Data
(Immunohistochemical staining of growth cones of primary olfactory neurons within the olfactory bulb in the developing rat brain using Mouse anti growth cone antibody)
Mouse anti-Mouse, Rat GROWTH CONE Monoclonal Antibody | anti-RPSA antibody
MOUSE ANTI GROWTH CONE
Gene Names
RPSA; 67LR; lamR; 37LRP; DMRT1; LRP/LR; LBP/p40
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry
Synonyms
GROWTH CONE; Monoclonal Antibody; MOUSE ANTI GROWTH CONE; anti-RPSA antibody
Host
Mouse
Reactivity
Mouse, Rat
Clonality
Monoclonal
Isotype
IgM
Clone Number
2G13
Form/Format
Tissue Culture Supernatant - liquid
Sequence Length
296
Applicable Applications for anti-RPSA antibody
Immunohistology Frozen, Immunohistology Paraffin
Application Notes
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Perservative Stabilisers
0.09% Sodium Azide
Target Species
Chicken
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Testing Data
(Immunohistochemical staining of growth cones of primary olfactory neurons within the olfactory bulb in the developing rat brain using Mouse anti growth cone antibody)
Testing Data
(Immunohistochemical staining of growth cones of primary olfactory neurons within the olfactory bulb in the developing rat brain using Mouse anti growth cone antibody)
Related Product Information for anti-RPSA antibody
Mouse anti Growth Cone antibody, clone 2G13 recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kDa laminin receptor precursor or Laminin receptor 1 (Baloui et al. 2004). 40S ribosomal protein SA is a 296 amino acid ~37kDa membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit.. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor (UniProt: P50890). In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture (Stettler et al. 1999). 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility (Stettler et al. 1999). Mouse anti Growth Cone antibody, clone 2G13 has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples (Baloui et al. 2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,021 Da
NCBI Official Full Name
40S ribosomal protein SA
NCBI Official Synonym Full Names
ribosomal protein SA
NCBI Official Symbol
RPSA
NCBI Official Synonym Symbols
67LR; lamR; 37LRP; DMRT1; LRP/LR; LBP/p40
NCBI Protein Information
40S ribosomal protein SA; 37LRP; 37kD Laminin receptor; 67LR; LBP/p40; LRP/LR; RPSA; lamR
UniProt Protein Name
40S ribosomal protein SA
Protein Family
UniProt Gene Name
RPSA
UniProt Entry Name
RSSA_CHICK
Uniprot Description
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
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Product Notes
The RPSA rpsa (Catalog #AAA215161) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI GROWTH CONE reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GROWTH CONE can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Immunohistology Paraffin. Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Researchers should empirically determine the suitability of the RPSA rpsa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GROWTH CONE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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