Mouse Glucocorticoid Modulatory Element Binding Protein 2 Monoclonal Antibody | anti-GMEB2 antibody

Glucocorticoid Modulatory Element Binding Protein 2 (GMEB2, KIAA1269, P79PIF, PIF79)

Cat. Num. AAA602959

• Gene Names: GMEB2; PIF79; P79PIF; KIAA1269
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Glucocorticoid Modulatory Element Binding Protein 2; Monoclonal Antibody; Glucocorticoid Modulatory Element Binding Protein 2 (GMEB2; KIAA1269; P79PIF; PIF79); Anti -Glucocorticoid Modulatory Element Binding Protein 2 (GMEB2; anti-GMEB2 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: 8C167
• Specificity: Recognizes human Glucocorticoid Modulatory Element Binding Protein 2.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-GMEB2 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human Glucocorticoid Modulatory Element Binding Protein 2
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-GMEB2 antibody

Antibodies; Abs to Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 6912568
• NCBI GeneID: 26205
• NCBI Accession #: NP_036516.1
• NCBI GenBank Nucleotide #: NM_012384.3
• UniProt Accession #: Q9UKD1; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9ULF1; E1P5J3; Q659E7
• Molecular Weight: 56,421 Da
• NCBI Official Full Name: glucocorticoid modulatory element-binding protein 2
• NCBI Official Synonym Full Names: glucocorticoid modulatory element binding protein 2
• NCBI Official Symbol: GMEB2
• NCBI Official Synonym Symbols: PIF79; P79PIF; KIAA1269
• NCBI Protein Information: glucocorticoid modulatory element-binding protein 2; GMEB-2; PIF p79; OTTHUMP00000031573; OTTHUMP00000031574; OTTHUMP00000031575; DNA-binding protein p79PIF; parvovirus initiation factor p79; parvovirus initiation factor, p79
• UniProt Protein Name: Glucocorticoid modulatory element-binding protein 2
• Protein Family: Glucocorticoid modulatory element-binding protein
• UniProt Gene Name: GMEB2
• UniProt Synonym Gene Names: KIAA1269
• UniProt Entry Name: GMEB2_HUMAN

NCBI Description

This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. [provided by RefSeq]

Uniprot Description

GMEB2: Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: DNA binding; metal ion binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent