Western Blot (WB)
(Western blot analysis of GLT Monoclonal Antibody in A375 cell line lysates. GLT (arrow) was detected using the ascites Mab. (dilution 1:1000))
Mouse anti-Human GLT Monoclonal Antibody | anti-LGALS1 antibody
GLT Antibody
Western Blot (WB)
(Western blot analysis of GLT Monoclonal Antibody in A375 cell line lysates. GLT (arrow) was detected using the ascites Mab. (dilution 1:1000))
Western Blot (WB)
(Western blot analysis of GLT Monoclonal Antibody in A375 cell line lysates. GLT (arrow) was detected using the ascites Mab. (dilution 1:1000))
NCBI and Uniprot Product Information
NCBI Description
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]
Uniprot Description
Galectin-1: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin (via poly-N- acetyllactosamine). Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion. Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cell surface; cytoplasm; intracellular; nucleus
Molecular Function: signal transducer activity; protein binding; protein homodimerization activity; lactose binding; galactoside binding; laminin binding; glycoprotein binding
Biological Process: regulation of apoptosis; myoblast differentiation; response to drug; plasma cell differentiation; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptosis; T cell costimulation; positive regulation of erythrocyte aggregation; response to axon injury; signal transduction; multicellular organismal response to stress
Research Articles on LGALS1
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Product Notes
The LGALS1 lgals1 (Catalog #AAA9200105) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GLT Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the LGALS1 lgals1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLT, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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