Immunohistochemistry (IHC)
(Anti-GIPC1 / GIPC antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Mouse anti-Human GIPC1 / GIPC Monoclonal Antibody | anti-GIPC1 antibody
Mouse Monoclonal [clone AT1G10] (IgG1,k) to Human GIPC1 / GIPC
Immunohistochemistry (IHC)
(Anti-GIPC1 / GIPC antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GIPC1 / GIPC antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GIPC antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The cross-reacting of anti-human GIPC (AT1G10) were analyzed by using recombinant protein(20ng) of GIPC1 and GIPC2.)
Western Blot (WB)
(Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GIPC antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The cross-reacting of anti-human GIPC (AT1G10) were analyzed by using recombinant protein(20ng) of GIPC1 and GIPC2.)
NCBI and Uniprot Product Information
NCBI Description
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
Uniprot Description
GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; GAPs; GAPs, misc.; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: synaptic vesicle; membrane; endocytic vesicle; cytoplasmic membrane-bound vesicle; cytoplasm; dendritic spine; vesicle membrane; cell cortex; dendritic shaft; cytosol; brush border
Molecular Function: protein binding; protein homodimerization activity; myosin binding; actin binding; receptor binding; PDZ domain binding
Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; synaptic transmission; glutamate secretion; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of protein stability; endothelial cell migration; regulation of synaptic plasticity; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; protein targeting
Research Articles on GIPC1
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Product Notes
The GIPC1 gipc1 (Catalog #AAA249164) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone AT1G10] (IgG1,k) to Human GIPC1 / GIPC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GIPC1 / GIPC can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (10 ug/ml), WB (1:1000). Researchers should empirically determine the suitability of the GIPC1 gipc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GIPC1 / GIPC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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