Mouse anti-Human GBP2 Monoclonal Antibody | anti-GBP2 antibody

GBP2 (Interferon-induced Guanylate-binding Protein 2, GTP-binding Protein 2, GBP-2, HuGBP-2, Guanine Nucleotide-binding Protein 2) (FITC)

Cat. Num. AAA6147341

• Reactivity: Human
• Applications: ELISA, Immunoprecipitation, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GBP2; Monoclonal Antibody; GBP2 (Interferon-induced Guanylate-binding Protein 2; GTP-binding Protein 2; GBP-2; HuGBP-2; Guanine Nucleotide-binding Protein 2) (FITC); anti-GBP2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 2A10
• Specificity: Recognizes human GBP2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 1743

• Applicable Applications for anti-GBP2 antibody: ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-481 from human GBP2 (AAH22272) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLS
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (78.65kD).)

Western Blot (WB)

(Western Blot analysis of GBP2 expression in transfected 293T cell line by GBP2 monoclonal antibody. Lane 1: GBP2 transfected lysate (67.2kD). Lane 2: Non-transfected lysate.)

Immunoprecipitation (IP)

(Immunoprecipitation of GBP2 transfected lysate using GBP2 monoclonal antibody and Protein A Magnetic Bead and immunoblotted with GBP2 rabbit polyclonal antibody.)

Related Product Information for anti-GBP2 antibody

Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

Product Categories/Family for anti-GBP2 antibody

Antibodies; Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 18490137
• NCBI GeneID: 2634
• NCBI Official Full Name: Homo sapiens guanylate binding protein 2, interferon-inducible, mRNA
• NCBI Official Synonym Full Names: guanylate binding protein 2
• NCBI Official Symbol: GBP2
• NCBI Protein Information: guanylate-binding protein 2
• Protein Family: Guanylate-binding protein

NCBI Description

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]