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Immunohistochemistry (IHC)
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Mouse anti-Human Gastrin Monoclonal Antibody | anti-GAST antibody

Gastrin Mouse mAb

Gene Names
GAST; GAS
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
Gastrin; Monoclonal Antibody; Gastrin Mouse mAb; gastrin; anti-GAST antibody
Ordering
 
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For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3, kappa
Specificity
This antibody detects endogenous levels of human Gastrin
Purity/Purification
Affinity Chromatography
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-GAST antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-1:500
Immunogen
Synthesized peptide derived from human Gastrin
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Stomach. 1, Antibody was diluted at 1:200(4 degree ,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).)

Related Product Information for anti-GAST antibody
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
Product Categories/Family for anti-GAST antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,394 Da
NCBI Official Full Name
gastrin preproprotein
NCBI Official Synonym Full Names
gastrin
NCBI Official Symbol
GAST
NCBI Official Synonym Symbols
GAS
NCBI Protein Information
gastrin; preprogastrin
UniProt Protein Name
Gastrin
Protein Family
UniProt Gene Name
GAST
UniProt Synonym Gene Names
GAS; G52; G34; G17; G14; G6
UniProt Entry Name
GAST_HUMAN

NCBI Description

Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]

Uniprot Description

gastrin: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Belongs to the gastrin/cholecystokinin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction

Research Articles on GAST

1. A novel signal pathway involved in gastrin-stimulated AE2 expression mediated by EGR1 in gastric cancer cells.

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Product Notes

The GAST gast (Catalog #AAA4753929) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Gastrin Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Gastrin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-1:500. Researchers should empirically determine the suitability of the GAST gast for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Gastrin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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