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Mouse G-CSFR Monoclonal Antibody | anti-G-CSFR antibody

mAb anti-Human G-CSFR

Gene Names
CSF3R; CD114; GCSFR
Reactivity
Human. Other species not tested
Applications
Western Blot
Purity
Protein G affinity purified
Synonyms
G-CSFR; Monoclonal Antibody; mAb anti-Human G-CSFR; Granulocyte-Colony Stimulating Factor Receptor (G-CSFR); Mouse monoclonal antibody to human granulocyte colony stimulating factor receptor (G-CSFR); anti-G-CSFR antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human. Other species not tested
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
S-1374
Specificity
Reactive with G-CSFR and does not cross-react with MBP or BSA (bovine serum albumin)
Granulocyte-Colony Stimulating Factor Receptor (G-CSFR)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.2.
Sequence Length
771
Applicable Applications for anti-G-CSFR antibody
Western Blot (WB)
Application Notes
Western Blot: The antibody, when used at concentration of 1-10mug/mL will allow visualization of 250ng/lane of human G-CSFR-MBP.
The antibody recognizes denatured G-CSFR in Western blot following SDS-PAGE. Suggest use 200mug of cell lysate or immunoprecipitated protein.
Target Protein
Human G-CSFR
Immunogen
Purified recombinant MBP-GCSFR fusion protein
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Research Area
Cytokine receptor. Hematopoiesis
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-G-CSFR antibody
Mouse monoclonal antibody to human granulocyte colony stimulating factor receptor (G-CSFR), Protein G affinity purified
Product Categories/Family for anti-G-CSFR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
86,609 Da
NCBI Official Full Name
granulocyte colony-stimulating factor receptor
NCBI Official Synonym Full Names
colony stimulating factor 3 receptor (granulocyte)
NCBI Official Symbol
CSF3R
NCBI Official Synonym Symbols
CD114; GCSFR
NCBI Protein Information
granulocyte colony-stimulating factor receptor; CD114 antigen; G-CSF receptor; G-CSF-R
UniProt Protein Name
Granulocyte colony-stimulating factor receptor
UniProt Gene Name
CSF3R
UniProt Entry Name
CSF3R_HUMAN

NCBI Description

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]

Uniprot Description

GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p35-p34.3

Cellular Component: integral to plasma membrane; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity

Biological Process: neutrophil chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; signal transduction; cell adhesion

Disease: Neutrophilia, Hereditary

Research Articles on G-CSFR

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Product Notes

The G-CSFR csf3r (Catalog #AAA592187) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human G-CSFR reacts with Human. Other species not tested and may cross-react with other species as described in the data sheet. AAA Biotech's G-CSFR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: The antibody, when used at concentration of 1-10mug/mL will allow visualization of 250ng/lane of human G-CSFR-MBP. The antibody recognizes denatured G-CSFR in Western blot following SDS-PAGE. Suggest use 200mug of cell lysate or immunoprecipitated protein. . Researchers should empirically determine the suitability of the G-CSFR csf3r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "G-CSFR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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