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Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant FRK protein using FRK antibody)

Mouse FRK Monoclonal Antibody | anti-FRK antibody

FRK antibody

Gene Names
FRK; GTK; RAK; PTK5
Applications
Flow Cytometry, Functional Assay, Immunofluorescence
Purity
FRK antibody was purified by affinity chromatography.
Synonyms
FRK; Monoclonal Antibody; FRK antibody; Monoclonal FRK; Anti-FRK; Fyn-Related Kinase; GTK; PTK5; RAK; anti-FRK antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5F3
Purity/Purification
FRK antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
505
Applicable Applications for anti-FRK antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes
FC: 1:100
IF: 1:100
Biological Significance
FRK is an epithelial tissue-specific kinase. The human FRK gene maps to chromosome 6q21-q22. 3 and encodes a 505 amino acid protein. The protein belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
Cross-Reactivity
Human
Immunogen
FRK antibody was raised in mouse using a full length recombinant protein of human FRK (NP_002022) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescent staining of COS7 cells transiently transfected with recombinant FRK protein using FRK antibody)

Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant FRK protein using FRK antibody)
Related Product Information for anti-FRK antibody
Mouse monoclonal FRK antibody
Product Categories/Family for anti-FRK antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,980 Da
NCBI Official Full Name
tyrosine-protein kinase FRK
NCBI Official Synonym Full Names
fyn-related Src family tyrosine kinase
NCBI Official Symbol
FRK
NCBI Official Synonym Symbols
GTK; RAK; PTK5
NCBI Protein Information
tyrosine-protein kinase FRK
UniProt Protein Name
Tyrosine-protein kinase FRK
Protein Family
UniProt Gene Name
FRK
UniProt Synonym Gene Names
PTK5; RAK
UniProt Entry Name
FRK_HUMAN

NCBI Description

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

Uniprot Description

FRK: a tyrosine kinase of the Src family. Expressed in cell lines derived from tissues of lymphoid, brain, breast, colon and bladder origin. A nuclear protein that may function during G1 and S phase of the cell cycle to suppress growth.

Protein type: Tumor suppressor; Protein kinase, TK; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Kinase, protein; TK group; Src family

Chromosomal Location of Human Ortholog: 6q21-q22.3

Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; intracellular; nucleus

Molecular Function: protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding

Biological Process: negative regulation of cell proliferation; cell migration; innate immune response; cell differentiation; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

Research Articles on FRK

Similar Products

Product Notes

The FRK frk (Catalog #AAA830607) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FRK can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF). FC: 1:100 IF: 1:100. Researchers should empirically determine the suitability of the FRK frk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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