Mouse anti-Human Formyl Peptide-Receptor-Like-1 Monoclonal Antibody | anti-FPR2 antibody
Formyl Peptide-Receptor-Like-1 (FPRL1)
Gene Names
FPR2; ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
Reactivity
Human
Applications
ELISA, Western Blot
Purity
PurifiedPurified by Protein G affinity chromatography.
Synonyms
Formyl Peptide-Receptor-Like-1; Monoclonal Antibody; Formyl Peptide-Receptor-Like-1 (FPRL1); Anti -Formyl Peptide-Receptor-Like-1 (FPRL1); anti-FPR2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
12K262
Specificity
Recognizes the amino acid sequence of the 2nd extracellular loop of human FPRL1 and intact human FPRL1.
Purity/Purification
Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from 0.01M PBS, pH7.2. Reconstitute in sterile dH2O to a concentration of 1mg/ml.
Applicable Applications for anti-FPR2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:2000
Dilution: Western Blot: 1:2000
Immunogen
The amino acid sequence of the 2nd extracellular loop of human FPRL1, (KLH).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-FPR2 antibody
FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.
Product Categories/Family for anti-FPR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
38,964 Da
NCBI Official Full Name
formyl peptide receptor-like 1
NCBI Official Synonym Full Names
formyl peptide receptor 2
NCBI Official Symbol
FPR2
NCBI Official Synonym Symbols
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
NCBI Protein Information
N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)
UniProt Protein Name
N-formyl peptide receptor 2
Protein Family
UniProt Gene Name
FPR2
UniProt Synonym Gene Names
FPRH1; FPRL1; LXA4R; FMLP-R-I
UniProt Entry Name
FPR2_HUMAN
Uniprot Description
FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion; chemotaxis; cell motility; inflammatory response
Research Articles on FPR2
Similar Products
Product Notes
The FPR2 fpr2 (Catalog #AAA6007905) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Formyl Peptide-Receptor-Like-1 (FPRL1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Formyl Peptide-Receptor-Like-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:2000. Researchers should empirically determine the suitability of the FPR2 fpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Formyl Peptide-Receptor-Like-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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