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Immunohistochemistry (Immunohistochemical staining using Follicular Dendritic Cells antibodyRat spleen frozen tissue section)

Mouse anti-Rat Follicular Dendritic Cells Monoclonal Antibody | anti-FDCSP antibody

Follicular Dendritic Cells antibody

Gene Names
FDCSP; C4orf7; FDC-SP
Reactivity
Rat
Applications
Immunohistochemistry
Synonyms
Follicular Dendritic Cells; Monoclonal Antibody; Follicular Dendritic Cells antibody; Monoclonal Follicular Dendritic Cells; Anti-Follicular Dendritic Cells; anti-FDCSP antibody
Ordering
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
KI-M9R
Specificity
Rat
Form/Format
Affinity purified antibody supplied lyophilized from PBS, pH 7.2, with 5mg/mL BSA as a stabilizer and 0.05% NaN3 as a preservative. Reconstitute with 0.5ml distilled water.
Concentration
500 ug, Lyophilized (varies by lot)
Sequence Length
85
Applicable Applications for anti-FDCSP antibody
Immunohistochemistry (IHC) Formalin/Paraffin
Application Notes
IHC-F: 5 ug/ml
IHC-P: 50 ug/ml
Biological Significance
Dendritic cells (DCs) are immune cells forming part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system. That is, they function as antigen-presenting cells. They act as messengers between the innate and adaptive immunity.
Immunogen
Folllicular dendritic cells antibody was raised in mouse using rat peritoneal macrophages as the immunogen.
Preparation and Storage
Upon receipt store at 4°C while lyophilized. After reconstituted, store at 4°C short term, -20°C long term. Avoid repeat freeze-thaws.

Immunohistochemistry

(Immunohistochemical staining using Follicular Dendritic Cells antibodyRat spleen frozen tissue section)

Immunohistochemistry (Immunohistochemical staining using Follicular Dendritic Cells antibodyRat spleen frozen tissue section)
Related Product Information for anti-FDCSP antibody
Mouse monoclonal Follicular Dendritic Cells antibody
Product Categories/Family for anti-FDCSP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
follicular dendritic cell secreted peptide
NCBI Official Synonym Full Names
follicular dendritic cell secreted protein
NCBI Official Symbol
FDCSP
NCBI Official Synonym Symbols
C4orf7; FDC-SP
NCBI Protein Information
follicular dendritic cell secreted peptide
UniProt Protein Name
Follicular dendritic cell secreted peptide
UniProt Gene Name
FDCSP
UniProt Synonym Gene Names
C4orf7; FDC secreted protein; FDC-SP
UniProt Entry Name
FDSCP_HUMAN

NCBI Description

This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011]

Uniprot Description

FDCSP: Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q13|4q13

Cellular Component: extracellular region

Research Articles on FDCSP

Similar Products

Product Notes

The FDCSP fdcsp (Catalog #AAA532042) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Follicular Dendritic Cells antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Follicular Dendritic Cells can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Formalin/Paraffin. IHC-F: 5 ug/ml IHC-P: 50 ug/ml. Researchers should empirically determine the suitability of the FDCSP fdcsp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Follicular Dendritic Cells, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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