Western Blot (WB)
(Western Blot analysis of Human kidney tissue using Fibromodulin Monoclonal Antibody at dilution of 1:250)
Mouse anti-Human, Mouse FMOD Monoclonal Antibody | anti-FMOD antibody
FMOD Monoclonal Antibody
Gene Names
FMOD; FM; SLRR2E
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Caprylic acid/ammonium sulfate precipitation
Synonyms
FMOD; Monoclonal Antibody; FMOD Monoclonal Antibody; Collagen binding 59 kDa protein; Collagen-binding 59 kDa protein; Fibromodulin; Fibromodulin precursor; Fibromodulin proteoglycan; FM; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; SLRR2E; anti-FMOD antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
770
Purity/Purification
Caprylic acid/ammonium sulfate precipitation
Concentration
1mg/mL (varies by lot)
Sequence Length
376
Applicable Applications for anti-FMOD antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:200-1:2000
IHC: 1:20-1:200
IHC: 1:20-1:200
Immunogen
Fusion protein of Fibromodulin
Buffer
PBS with 0.1% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Human kidney tissue using Fibromodulin Monoclonal Antibody at dilution of 1:250)
Western Blot (WB)
(Western Blot analysis of Human kidney tissue using Fibromodulin Monoclonal Antibody at dilution of 1:250)
Related Product Information for anti-FMOD antibody
Fibromodulin (FMOD), an extracellular matrix protein, belongs to the small leucine-rich proteoglycan family. Fibromodulin is a collagen-binding protein present in many types of connective tissues, e.g. cartilage, tendon, skin, sclera and cornea. It is involved in fibrillogenesis, cell adhesion, and cytokine activity modulation. Fibromodulin may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. The calculated molecular mass of fibromodulin is 43 kDa, extracellular fibromodulin appears as one single band of 59 kDa due to glycosylation.
Product Categories/Family for anti-FMOD antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 43kDa
Observed: 59kDa
Observed: 59kDa
NCBI Official Full Name
fibromodulin
NCBI Official Synonym Full Names
fibromodulin
NCBI Official Symbol
FMOD
NCBI Official Synonym Symbols
FM; SLRR2E
NCBI Protein Information
fibromodulin
UniProt Protein Name
Fibromodulin
Protein Family
UniProt Gene Name
FMOD
UniProt Synonym Gene Names
FM; SLRR2E; FM; KSPG fibromodulin
NCBI Description
Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot Description
Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis ().
Research Articles on FMOD
Similar Products
Product Notes
The FMOD fmod (Catalog #AAA2541914) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FMOD Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FMOD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:200-1:2000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the FMOD fmod for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMOD, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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