Western Blot (WB)
(HT-1080 cells were subjected to SDS PAGE followed by western blot with MBS769325 (FGF18 Antibody) at dilution of 1:1000)
Mouse anti-Human, Mouse FGF18 Monoclonal Antibody | anti-FGF18 antibody
FGF18 Mouse Monoclonal
Protein A+G purification
Protein A+G purification
Western Blot (WB)
(HT-1080 cells were subjected to SDS PAGE followed by western blot with MBS769325 (FGF18 Antibody) at dilution of 1:1000)
Western Blot (WB)
(HT-1080 cells were subjected to SDS PAGE followed by western blot with MBS769325 (FGF18 Antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]
Uniprot Description
FGF18: Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 5q34
Cellular Component: extracellular region; extracellular space; nucleolus
Molecular Function: 1-phosphatidylinositol-3-kinase activity; growth factor activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; type 1 fibroblast growth factor receptor binding; type 2 fibroblast growth factor receptor binding
Biological Process: anatomical structure morphogenesis; angiogenesis; cell-cell signaling; chondrocyte development; endochondral ossification; fibroblast growth factor receptor signaling pathway; intramembranous ossification; lung development; MAPKKK cascade; peptidyl-tyrosine phosphorylation; phosphoinositide phosphorylation; phosphoinositide-mediated signaling; positive regulation of cell proliferation; positive regulation of chondrocyte differentiation; positive regulation of GTPase activity; positive regulation of MAP kinase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; regulation of endothelial cell proliferation; regulation of phosphoinositide 3-kinase cascade; signal transduction
Research Articles on FGF18
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Product Notes
The FGF18 fgf18 (Catalog #AAA769325) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FGF18 Mouse Monoclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FGF18 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the FGF18 fgf18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGF18, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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