Western Blot (WB)
(Figure 1: Western blot analysis using FBLN2 mouse mAb against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).)
Mouse anti-Human FBLN2 Monoclonal Antibody | anti-FBLN2 antibody
FBLN2 Antibody
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-Chromatography
Synonyms
FBLN2; Monoclonal Antibody; FBLN2 Antibody; Fbln2; FBLN2_HUMAN; FIBL-2; Fibulin-2; OTTHUMP00000216670; OTTHUMP00000216671; OTTHUMP00000216672; anti-FBLN2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Specificity
FBLN2 antibody detects endogenous levels of total FBLN2
Purity/Purification
Affinity-Chromatography
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1231
Applicable Applications for anti-FBLN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
ELISA: 1:10000
WB: 1:500-1:2000
WB: 1:500-1:2000
Immunogen
Purified recombinant fragment of human FBLN2 expressed in E. Coli
Subcellular Location
Secreted > Extracellular Space > Extracellular Matrix.
Tissue Specificity
Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Figure 1: Western blot analysis using FBLN2 mouse mAb against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).)
Western Blot (WB)
(Figure 1: Western blot analysis using FBLN2 mouse mAb against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).)
Related Product Information for anti-FBLN2 antibody
Description: This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.
Function: Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Subunit Structure: Homotrimer; disulfide-linked. Interacts with LAMA2 (By similarity). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108).
Post-translational Modifications: O-glycosylated with core 1 or possibly core 8 glycans. It is unsure if the O-glycosylation is on Thr-347 or Ser-348.
Similarity: Belongs to the fibulin family.
Function: Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Subunit Structure: Homotrimer; disulfide-linked. Interacts with LAMA2 (By similarity). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108).
Post-translational Modifications: O-glycosylated with core 1 or possibly core 8 glycans. It is unsure if the O-glycosylation is on Thr-347 or Ser-348.
Similarity: Belongs to the fibulin family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 127 kDa
Predicted: 127 kDa
Predicted: 127 kDa
NCBI Official Full Name
fibulin-2 isoform a
NCBI Official Synonym Full Names
fibulin 2
NCBI Official Symbol
FBLN2
NCBI Protein Information
fibulin-2
UniProt Protein Name
Fibulin-2
Protein Family
UniProt Gene Name
FBLN2
UniProt Synonym Gene Names
FIBL-2
NCBI Description
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Research Articles on FBLN2
Similar Products
Product Notes
The FBLN2 fbln2 (Catalog #AAA9602433) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FBLN2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FBLN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). ELISA: 1:10000 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the FBLN2 fbln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBLN2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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