Flow Cytometry (FC/FACS)
(Flow Cytometry Analysis: Representative lot data. Staining of HUVEC cells with A 1:200 dilution of Endoglin (CD105) or with 1ug of Mouse IgG1 isotype control.)
Mouse anti-Human Endoglin Monoclonal Antibody | anti-END antibody
Endoglin (CD105, ENG, END) (MaxLight 490)
Gene Names
ENG; END; HHT1; ORW1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation
Purity
Purified by Protein G Affinity Chromatography
Synonyms
Endoglin; Monoclonal Antibody; Endoglin (CD105; ENG; END) (MaxLight 490); anti-END antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
13A178
Specificity
Recognizes human CD105.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-END antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
Whole HOON Pre-B Leukemic cells.
Conjugate
MaxLight490
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Flow Cytometry (FC/FACS)
(Flow Cytometry Analysis: Representative lot data. Staining of HUVEC cells with A 1:200 dilution of Endoglin (CD105) or with 1ug of Mouse IgG1 isotype control.)
Flow Cytometry (FC/FACS)
(Flow Cytometry Analysis: Representative lot data. Staining of HUVEC cells with A 1:200 dilution of Endoglin (CD105) or with 1ug of Mouse IgG1 isotype control.)
Product Categories/Family for anti-END antibody
References
1. Gougos, A., and Letarte, M. (1988). J Immunol. 141(6):1925-1933. 2. Rodriquez-Pena, A., et al. (2002). Hypertension. 40(5): 713-720. 3. Ge, A.Z., and Butcher, E.C. (1994). Gene. 138(1-2):201-206. 4. Kruse, A., et al. (1999). Biol Reprod. 61(6): 1393-1401. 5. Ringlemann, B., et al. (1999). Exp Cell Res. 246(1):165-182. 6. Vajkoczy, P., et al. (2003). J Exp Med. 197(12): 1755-1765. 7. Finley, M.F., et al. (1999). J Neurobiol. 40(3): 271-287. 8. Lidington, E.A., et al. (2002). Am J Physiol Cell Physiol. 282(1):C67-74. 9. Izawa, D., et al. (1999). Int Immunol. 11(12): 1989-1998. 10. Raab, U., et al. (1999). Biochem J. 339(Pt3): 579-588. 11. Garton, K.J., et al. (2003). J Biol Chem. 278(39):37589-37464.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64.9 kDa (594aa)
NCBI Official Full Name
endoglin isoform 2
NCBI Official Synonym Full Names
endoglin
NCBI Official Symbol
ENG
NCBI Official Synonym Symbols
END; HHT1; ORW1
NCBI Protein Information
endoglin
UniProt Protein Name
Endoglin
Protein Family
UniProt Gene Name
ENG
UniProt Synonym Gene Names
END
UniProt Entry Name
EGLN_HUMAN
NCBI Description
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Research Articles on END
Similar Products
Product Notes
The END eng (Catalog #AAA6245718) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Endoglin (CD105, ENG, END) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Endoglin can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the END eng for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endoglin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
