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Western Blot (WB) (Fig-1: Western blot analysis of mEBI3. Anti-mEBI3 antibody (Clone: ABM2C40) was tested at 2 ug/ml on m Small Intestine lysate.)

Rat anti-Mouse EBI3 Monoclonal Antibody | anti-Ebi3 antibody

Monoclonal Antibody to EBI3 Mouse (Clone: ABM2C40)

Gene Names
Ebi3; EBI-3; IL-27
Reactivity
Mouse
Applications
Western Blot
Purity
Purified
Protein G Chromatography
Synonyms
EBI3; Monoclonal Antibody; Monoclonal Antibody to EBI3 Mouse (Clone: ABM2C40); Ebi3; Il27b; Epstein-Barr virus-induced gene 3 protein homolog; Antibody to EBI3 Mouse; Anti-EBI3 Mouse Antibody; EBI3 Mouse Antibody; anti-Ebi3 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
ABM2C40
Purity/Purification
Purified
Protein G Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
228
Applicable Applications for anti-Ebi3 antibody
Western Blot (WB)
Application Notes
WB: 2-4 ug/ml
Immunogen Information
A full length recombinant mEBI3 protein was used as the immunogen for this antibody.
Antigen
EBI3 Mouse
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Western Blot (WB)

(Fig-1: Western blot analysis of mEBI3. Anti-mEBI3 antibody (Clone: ABM2C40) was tested at 2 ug/ml on m Small Intestine lysate.)

Western Blot (WB) (Fig-1: Western blot analysis of mEBI3. Anti-mEBI3 antibody (Clone: ABM2C40) was tested at 2 ug/ml on m Small Intestine lysate.)
Related Product Information for anti-Ebi3 antibody
Epstein-Barr Virus?Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.
Product Categories/Family for anti-Ebi3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
25,353 Da
NCBI Official Full Name
Interleukin-27 subunit beta
NCBI Official Synonym Full Names
Epstein-Barr virus induced gene 3
NCBI Official Symbol
Ebi3
NCBI Official Synonym Symbols
EBI-3; IL-27
NCBI Protein Information
interleukin-27 subunit beta
UniProt Protein Name
Interleukin-27 subunit beta
Protein Family
UniProt Gene Name
Ebi3
UniProt Synonym Gene Names
Il27b; IL-27 subunit beta; IL-27B

Uniprot Description

IL27-beta: Cytokine with pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon- gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. Belongs to the type I cytokine receptor family. Type 3 subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17 D|17 29.08 cM

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-27 receptor binding; protein binding

Biological Process: T cell proliferation

Research Articles on Ebi3

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Product Notes

The Ebi3 ebi3 (Catalog #AAA668326) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to EBI3 Mouse (Clone: ABM2C40) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EBI3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 2-4 ug/ml. Researchers should empirically determine the suitability of the Ebi3 ebi3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EBI3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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