Western Blot
(Western Blot analysis using DNAJB2 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant DNAJB2 protein (Right) or empty vector (Left) detected with DNAJB2 antibody)
Mouse DNAJB2 Monoclonal Antibody | anti-DNAJB2 antibody
DNAJB2 antibody
Western Blot
(Western Blot analysis using DNAJB2 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant DNAJB2 protein (Right) or empty vector (Left) detected with DNAJB2 antibody)
Western Blot
(Western Blot analysis using DNAJB2 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant DNAJB2 protein (Right) or empty vector (Left) detected with DNAJB2 antibody)
NCBI and Uniprot Product Information
NCBI Description
This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
Uniprot Description
DNAJB2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: proteasome complex; inclusion body; nucleus; cytosol
Molecular Function: protein binding; chaperone binding; unfolded protein binding; Hsp70 protein binding; polyubiquitin binding
Biological Process: negative regulation of cell proliferation; ER-associated protein catabolic process; protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein refolding; negative regulation of cell growth; response to unfolded protein
Disease: Spinal Muscular Atrophy, Distal, Autosomal Recessive, 5; Charcot-marie-tooth Disease, Axonal, Type 2t
Research Articles on DNAJB2
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Product Notes
The DNAJB2 dnajb2 (Catalog #AAA830679) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DNAJB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the DNAJB2 dnajb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJB2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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