Mouse anti-General Diglycyl Lysine Monoclonal Antibody
Diglycyl Lysine monoclonal antibody (GX41)
Reactivity
General
Applications
Immunoprecipitation, Western Blot
Purity
Protein G purified
Synonyms
Diglycyl Lysine; Monoclonal Antibody; Diglycyl Lysine monoclonal antibody (GX41); anti-Diglycyl Lysine antibody
Host
Mouse
Reactivity
General
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
GX41
Specificity
Recognizes diglycyl modified lysine, a ubiquitin remnant detectable after trypsin digestion
Purity/Purification
Protein G purified
Form/Format
Liquid. In PBS containing 0.1% sodium azide
Applicable Applications for anti-Diglycyl Lysine antibody
Immunoprecipitation (IP), Western Blot (WB)
Source Note
Purified from hybridoma tissue culture supernatant
Immunogen
Diglycine-modified histone from calf thymus, Type III-S, lysine rich fraction
Preparation and Storage
For long term storage, store at -20 degree C. Store unopened vial at -20 degree C until required for use. Store diluted antibody at 2-4 degree C and use within 1 month. Avoid freeze/thaw cycles
Shipping: Shipped on Blue Ice
Shipping: Shipped on Blue Ice
Related Product Information for anti-Diglycyl Lysine antibody
Protein ubiquitination is a fundamentally important post-translational modification that regulates myriad cell signaling pathways in eukaryotes. Alterations in protein ubiquitination have been linked to cancers and neurodegenerative, cardiovascular, immunological, and inflammatory diseases.
Identification of exact ubiquitinylation sites is challenging under physiological conditions, but the recent development of an immunoprecipitation approach allows for enrichment and identification of peptides derived from the ubiquitinated portion of proteins.
When ubiquitinated protein is digested with trypsin a diglycine residue remains at any lysine site of ubiquitin attachment. Diglycyl Lysine, mAb (GX41) facilitates easy capture and enrichment of peptides derived from ubiquitinated proteins by recognizing the diglycyl-lysine residue with no detectable reactivity to non modified lysines.
Identification of exact ubiquitinylation sites is challenging under physiological conditions, but the recent development of an immunoprecipitation approach allows for enrichment and identification of peptides derived from the ubiquitinated portion of proteins.
When ubiquitinated protein is digested with trypsin a diglycine residue remains at any lysine site of ubiquitin attachment. Diglycyl Lysine, mAb (GX41) facilitates easy capture and enrichment of peptides derived from ubiquitinated proteins by recognizing the diglycyl-lysine residue with no detectable reactivity to non modified lysines.
Product Categories/Family for anti-Diglycyl Lysine antibody
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Product Notes
The Diglycyl Lysine (Catalog #AAA565861) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Diglycyl Lysine monoclonal antibody (GX41) reacts with General and may cross-react with other species as described in the data sheet. AAA Biotech's Diglycyl Lysine can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the Diglycyl Lysine for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Diglycyl Lysine, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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