Mouse anti-Human DEPDC6 Monoclonal Antibody | anti-DEPTOR antibody

DEPDC6 (DEP Domain-containing mTOR-interacting Protein, DEP Domain-containing Protein 6, DEPTOR, DKFZp564B1778, FLJ12341, FLJ12428, FLJ13854)

Cat. Num. AAA6009495

• Gene Names: DEPTOR; DEP.6; DEPDC6
• Reactivity: Human
• Applications: ELISA
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: DEPDC6; Monoclonal Antibody; DEPDC6 (DEP Domain-containing mTOR-interacting Protein; DEP Domain-containing Protein 6; DEPTOR; DKFZp564B1778; FLJ12341; FLJ12428; FLJ13854); Anti -DEPDC6 (DEP Domain-containing mTOR-interacting Protein; anti-DEPTOR antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 5B3
• Specificity: Recognizes human DEPDC6.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEAEQLCHRLMEHGIIQHVSSKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQETHDSPFCLRKQSHDNRKSTSFMSVSPSKEIKTVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLHVDYRTVNNLILTGPRTIVMEVMEELEC

• Applicable Applications for anti-DEPTOR antibody: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA.
• Immunogen: Full length recombinant corresponding to aa1-410 from human DEPDC6 (AAH12040) with GST tag. MW of the GST tag alone is 26kD.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Testing Data

(Detection limit for recombinant GST tagged DEPDC6 is ~0.1ng/ml as a capture antibody.)

Related Product Information for anti-DEPTOR antibody

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

Product Categories/Family for anti-DEPTOR antibody

Antibodies; Abs to Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 545687835
• NCBI GeneID: 64798
• NCBI Accession #: NP_001269941.1
• NCBI GenBank Nucleotide #: NM_001283012.1
• UniProt Accession #: Q8TB45; Q96EQ1; Q9H0R7; Q9H894; Q9HA07; B2RCL9
• Molecular Weight: 46,294 Da
• NCBI Official Full Name: DEP domain-containing mTOR-interacting protein isoform 2
• NCBI Official Synonym Full Names: DEP domain containing MTOR-interacting protein
• NCBI Official Symbol: DEPTOR
• NCBI Official Synonym Symbols: DEP.6; DEPDC6
• NCBI Protein Information: DEP domain-containing mTOR-interacting protein; DEP domain containing 6; DEP domain-containing protein 6; DEP domain containing mTOR interacting protein
• UniProt Protein Name: DEP domain-containing mTOR-interacting protein
• Protein Family: DEP domain-containing mTOR-interacting protein
• UniProt Gene Name: DEPTOR
• UniProt Synonym Gene Names: DEPDC6
• UniProt Entry Name: DPTOR_HUMAN

Uniprot Description

DEPTOR: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 8q24.12

Cellular Component: intracellular

Molecular Function: protein binding

Biological Process: negative regulation of TOR signaling pathway; negative regulation of protein kinase activity; negative regulation of cell size