D-dimer mAb (Mouse anti-human, clone # C9)-Capture Ab Monoclonal Antibody

D-dimer (Capture Ab)

Cat. Num. AAA355005

• Reactivity: Human
• Applications: Western Blot, Lateral Flow, ELISA
• Purity: Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.; >95% by HPLC & SDS-PAGE
• Synonyms: D-dimer mAb (Mouse anti-human; clone # C9)-Capture Ab; Monoclonal Antibody; D-dimer (Capture Ab); Monoclonal Anti- D-dimer (Capture Ab); anti-D-dimer mAb (Mouse anti-human; clone # C9)-Capture Ab antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: C9
• Specificity: It specifically recognize human D-dimer antigen, and does not cross react with BSA and fibrinogen.
• Purity/Purification: Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.; >95% by HPLC & SDS-PAGE
• Form/Format: Liquid
• Concentration: 2.2 mg/ml (varies by lot)

• Applicable Applications for anti-D-dimer mAb (Mouse anti-human, clone # C9)-Capture Ab antibody: Western Blot (WB), Lateral Flow (LF), ELISA (EIA)
• Application Notes: WB, ELISA, Lateral flow assay (rapid test)
• Immunogen: Human D-dimer protein.
• Matched Antibody Pairs: Capture Ab: D-dimer mAb (clone # C9); Detection Ab: D-dimer mAb (clone # D10)
• Preparation and Storage: Aliquot and store at -20 degree C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Related Product Information for anti-D-dimer mAb (Mouse anti-human, clone # C9)-Capture Ab antibody

D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help identify thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the identification of the blood disorder disseminated intravascular coagulation.

References

1. Adam SS, Key NS, Greenberg CS (March 2009). "D-dimer antigen: current concepts and future prospects". Blood 113 (13): 2878-2887