Western Blot (WB)
(Western blotting detection of cytokeratin 8 in HeLa cell lysate by mouse monoclonal antibody C-51.)
Mouse Cytokeratin 8 Monoclonal Antibody | anti-KRT8 antibody
Anti-Cytokeratin 8 Purified
Gene Names
KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
Reactivity
Pig, Cow, Human, Sheep
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
Cytokeratin 8; Monoclonal Antibody; Anti-Cytokeratin 8 Purified; keratin 8; K8; CK8; CK-8; CYK8; KRT8; K2C8; CARD2; anti-KRT8 antibody
Host
Mouse
Reactivity
Pig, Cow, Human, Sheep
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C-51
Specificity
The mouse monoclonal antibody C-51 recognizes cytokeratin 8 (52.5 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
279
Applicable Applications for anti-KRT8 antibody
Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Cytoskeleton preparation from HeLa cells.
Negative Species
Dog, Mouse, Rat, Xenopus, Chicken, Rabbit
Preparation and Storage
Store at 2-8 degree C.
Western Blot (WB)
(Western blotting detection of cytokeratin 8 in HeLa cell lysate by mouse monoclonal antibody C-51.)
Western Blot (WB)
(Western blotting detection of cytokeratin 8 in HeLa cell lysate by mouse monoclonal antibody C-51.)
Related Product Information for anti-KRT8 antibody
Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
KRT8 protein
NCBI Official Synonym Full Names
keratin 8
NCBI Official Symbol
KRT8
NCBI Official Synonym Symbols
K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
NCBI Protein Information
keratin, type II cytoskeletal 8
Protein Family
NCBI Description
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Research Articles on KRT8
Similar Products
Product Notes
The KRT8 (Catalog #AAA1800481) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Cytokeratin 8 Purified reacts with Pig, Cow, Human, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the KRT8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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