Western Blot (WB)
(Western blot analysis of Cytokeratin 2e on human skin lysates using anti-Cytokeratin 2e antibody at 1/1, 000 dilution.)
Rabbit anti-Human Cytokeratin 2e Monoclonal Antibody | anti-KRT2 antibody
Cytokeratin 2e Antibody
Gene Names
KRT2; K2e; KRTE; CK-2e; KRT2A; KRT2E
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
ProA affinity purified
Synonyms
Cytokeratin 2e; Monoclonal Antibody; Cytokeratin 2e Antibody; CK 2e antibody; Cytokeratin-2e antibody; Epithelial keratin-2e antibody; K2e antibody; Keratin type II cytoskeletal 2 epidermal antibody; Keratin-2 epidermis antibody; KRT2 antibody; KRT2A antibody; KRT2E antibody; Type-II keratin Kb2 antibody; anti-KRT2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
JJ201-8
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-KRT2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Western Blot (WB)
(Western blot analysis of Cytokeratin 2e on human skin lysates using anti-Cytokeratin 2e antibody at 1/1, 000 dilution.)
Western Blot (WB)
(Western blot analysis of Cytokeratin 2e on human skin lysates using anti-Cytokeratin 2e antibody at 1/1, 000 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 2e antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 2e antibody. Counter stained with hematoxylin.)
Related Product Information for anti-KRT2 antibody
The keratin multigene family is made of "soft" epithelial cytokeratins and "hard" hair keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair keratins are responsible for creating nails and hair. There are two types of keratins: the acidic class I keratin proteins and the basic/neutral class II keratin proteins. Keratin 2 (KRT2), also known as Keratin type II cytoskeletal 2 epidermal, Keratin-2e (K2e), KRTE, Cytokeratin-2e (CK-2e), KRT2A or KRT2E, is a 639 amino acid class II epithelial Keratin protein belonging to the intermediate filament family. Encoded by a gene that maps to human chromosome 12q13.13, Keratin 2 functions in epidermal keratinocyte activation and proliferation, and plays a part in terminal cornification. Highly expressed in upper epithelial tissues, Keratin 2 forms heterotetramers with two class I Keratins and another class II Keratin. Defects in Keratin 2 have been linked to ichthyosis bullosa of Siemens (IBS), a rare autosomal dominant skin disorder.
Product Categories/Family for anti-KRT2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,433 Da
NCBI Official Full Name
keratin, type II cytoskeletal 2 epidermal
NCBI Official Synonym Full Names
keratin 2, type II
NCBI Official Symbol
KRT2
NCBI Official Synonym Symbols
K2e; KRTE; CK-2e; KRT2A; KRT2E
NCBI Protein Information
keratin, type II cytoskeletal 2 epidermal; cytokeratin-2e; epithelial keratin-2e; keratin-2 epidermis; type-II keratin Kb2
UniProt Protein Name
Keratin, type II cytoskeletal 2 epidermal
Protein Family
UniProt Gene Name
KRT2
UniProt Synonym Gene Names
KRT2A; KRT2E; CK-2e; K2e
UniProt Entry Name
K22E_HUMAN
Similar Products
Product Notes
The KRT2 krt2 (Catalog #AAA9435980) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 2e Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 2e can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the KRT2 krt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 2e, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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