Mouse Cytokeratin 20 Monoclonal Antibody | anti-KRT20 antibody
Cytokeratin 20 antibody
Reactivity
Human, Mouse, Pig, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Protein A affinity chromatography
Synonyms
Cytokeratin 20; Monoclonal Antibody; Cytokeratin 20 antibody; Monoclonal Cytokeratin 20; Anti-Cytokeratin 20; Cytokeratin -20; Keratin K20; anti-KRT20 antibody
Host
Mouse
Reactivity
Human, Mouse, Pig, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
IT-Ks20.10
Specificity
Human cytokeratin 20
Purity/Purification
Protein A affinity chromatography
Form/Format
Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)
Sequence Length
424
Applicable Applications for anti-KRT20 antibody
ELISA (EIA), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
Application Notes
IHC-F: 1:10
Biological Significance
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa.
Cross-Reactivity
Human, mouse, pig, rat
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
Cytokeratin 20 antibody was raised in mouse using electrophoretically purified cytokeratin 20 from human intestinal mucosa as the immunogen.
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-KRT20 antibody
Mouse monoclonal Cytokeratin 20 antibody
Product Categories/Family for anti-KRT20 antibody
NCBI and Uniprot Product Information
Uniprot Description
K20: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: cytoplasm; intermediate filament
Molecular Function: protein binding; structural constituent of cytoskeleton
Biological Process: regulation of protein secretion; apoptosis; cellular response to stress; intermediate filament organization
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Product Notes
The Cytokeratin 20 krt20 (Catalog #AAA531706) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 20 antibody reacts with Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 20 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB). IHC-F: 1:10. Researchers should empirically determine the suitability of the Cytokeratin 20 krt20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 20, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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