Immunohistochemistry (IHC)
(Immunohistochemical staining of breast carcinoma tissue using C8454-06A)
Mouse anti-Human, Mouse Cyclin D1 Monoclonal Antibody
Cyclin D1-PE
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Cyclin D1; Monoclonal Antibody; Cyclin D1-PE; anti-Cyclin D1 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3G112
Specificity
Recognizes cyclin D1. Does not crossreact with other cyclin proteins including other D type cyclins. Does not co-immunoprecipitate CDK4 kinase activity associated with cyclin D1. Species Crossreactivity: Human and mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-Cyclin D1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Full length human cyclin D1 protein.
Conjugate
PE
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Immunohistochemistry (IHC)
(Immunohistochemical staining of breast carcinoma tissue using C8454-06A)
Immunohistochemistry (IHC)
(Immunohistochemical staining of breast carcinoma tissue using C8454-06A)
Product Categories/Family for anti-Cyclin D1 antibody
References
1. Matsushine, H., et al; Identification and properties of an atypical catalytic subunit (p34PSKJ3/CDK4) for mammalian D-type G1 cyclins. Cell 71:323-334 (1992). 2. Baldin, V., et al; Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes & Dev. 7:812-821 (1993). 3. Xiong, Y., et al; D-type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71:505-514 (1992). 4. Kato, J-Y. et al; Direct binding of cyclin D to the retinoblastoma gene product (pRB) and pRB phosphorylation by the cyclin D-dependent kinase, CDK4. Genes & Dev. 7:331-342 (1993). 5. Serrano, M. et al; A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-707 (1993).
Similar Products
Product Notes
The Cyclin D1 (Catalog #AAA6258940) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cyclin D1-PE reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cyclin D1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the Cyclin D1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclin D1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
