Mouse Cyclin A Monoclonal Antibody | anti-CCNA antibody
Cyclin A (CCN1, CCNA, CCNA2, CCNA2_HUMAN, Cyclin A2) (AP)
ELISA: For coating, order antibody without BSA
IF: 1-2ug/ml
WB: 0.5-1ug/ml
IHC-F/P: 1-2ug/ml for 30 min at RT
Applications are based on unconjugated antibody.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008]
Uniprot Description
CCNA2: a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Protein type: Cell cycle regulation; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 4q27
Cellular Component: nucleoplasm; male pronucleus; cytoplasm; female pronucleus; nucleus
Molecular Function: protein binding; protein kinase binding
Biological Process: mitosis; positive regulation of fibroblast proliferation; organ regeneration; response to glucagon stimulus; cell division; positive regulation of transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of G2/M transition of mitotic cell cycle; Ras protein signal transduction; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; response to estradiol stimulus
Research Articles on CCNA
Similar Products
Product Notes
The CCNA ccna2 (Catalog #AAA6122980) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cyclin A (CCN1, CCNA, CCNA2, CCNA2_HUMAN, Cyclin A2) (AP) reacts with Bovine, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cyclin A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). IP: 1-2ug/500ug protein ELISA: For coating, order antibody without BSA IF: 1-2ug/ml WB: 0.5-1ug/ml IHC-F/P: 1-2ug/ml for 30 min at RT Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CCNA ccna2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclin A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
