Mouse anti-Human COXG/COX6B1 Monoclonal Antibody | anti-COXG/COX6B1 antibody

Anti-COXG/COX6B1 Antibody (clone 5D3)

Cat. Num. AAA2400572

• Gene Names: COX6B1; COXG; COX6B; COXVIb1
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Purified from ascites by Protein A
• Synonyms: COXG/COX6B1; Monoclonal Antibody; Anti-COXG/COX6B1 Antibody (clone 5D3); Mouse Monoclonal [clone 5D3] (IgG1; k) to Human COXG/COX6B1; COX6B1; COX6B; COXVIb1; COX VIb-1; COXG; anti-COXG/COX6B1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, k
• Clone Number: 5D3
• Purity/Purification: Purified from ascites by Protein A
• Form/Format: PBS, pH 7.4
• Sequence Length: 86

• Applicable Applications for anti-COXG/COX6B1 antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 5 ug/ml
• Immunogen: COX6B1 (NP_001854, 1 a.a. ~ 87 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.; Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-COX6B1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (WB)

(Anti-COX6B1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-COX6B1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(COX6B1 monoclonal antibody, clone 5D3 Western blot of COX6B1 expression in HL-60.)

Related Product Information for anti-COXG/COX6B1 antibody

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrialrespiratory chain, catalyzes the electron transfer from reducedcytochrome c to oxygen. It is a heteromeric complex consisting of 3catalytic subunits encoded by mitochondrial genes and multiplestructural subunits encoded by nuclear genes. the mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex.

NCBI and Uniprot Product Information

• NCBI GI #: 4502985
• NCBI GeneID: 1340
• NCBI Accession #: NP_001854.1
• NCBI GenBank Nucleotide #: NM_001863.4
• UniProt Accession #: P14854; Q6IBL4; B2R5C9
• Molecular Weight: 10,192 Da
• NCBI Official Full Name: cytochrome c oxidase subunit 6B1
• NCBI Official Synonym Full Names: cytochrome c oxidase subunit 6B1
• NCBI Official Symbol: COX6B1
• NCBI Official Synonym Symbols: COXG; COX6B; COXVIb1
• NCBI Protein Information: cytochrome c oxidase subunit 6B1
• UniProt Protein Name: Cytochrome c oxidase subunit 6B1
• UniProt Gene Name: COX6B1
• UniProt Synonym Gene Names: COX6B; COX VIb-1

NCBI Description

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]

Uniprot Description

Connects the two COX monomers into the physiological dimeric form.