Mouse anti-Human CORO1C Monoclonal Antibody | anti-CORO1C antibody

Anti-CORO1C Antibody (clone 1F7)

Cat. Num. AAA2400652

• Gene Names: CORO1C; HCRNN4
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Purified from ascites by Protein A
• Synonyms: CORO1C; Monoclonal Antibody; Anti-CORO1C Antibody (clone 1F7); Mouse Monoclonal [clone 1F7] (IgG2a; k) to Human CORO1C; CRNN4; Coronin 1C; Coronin-3; Coronin-1C; HCRNN4; anti-CORO1C antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a, k
• Clone Number: 1F7
• Specificity: Human CORO1C
• Purity/Purification: Purified from ascites by Protein A
• Form/Format: PBS, pH 7.4.
• Sequence Length: 474

• Applicable Applications for anti-CORO1C antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 3-5 ug/ml; WB: 1:500-1:1000
• Immunogen: CORO1C (NP_055140, 375 a.a. ~ 474 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C or lower.; Aliquot to avoid repeated freezing and thawing.

Immunohistochemistry (IHC)

(Anti-CORO1C/Coronin 3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.)

Western Blot (WB)

(Antibody Western blot of CORO1C expression in HeLa NE.)

ELISA (EIA)

(Detection limit for recombinant GST tagged CORO1C is 0.1 ng/ml as a capture antibody.)

Related Product Information for anti-CORO1C antibody

CORO1C is a member of the WD repeat protein family. WD repeats areminimally conserved regions of approximately 40 amino acids typicallybracketed by gly-his and trp-asp (GH-WD), which may facilitate formationof heterotrimeric or multiprotein complexes. Members of this family areinvolved in a variety of cellular processes, including cell cycleprogression, signal transduction, apoptosis, and gene regulation.

NCBI and Uniprot Product Information

• NCBI GI #: 7656991
• NCBI GeneID: 23603
• NCBI Accession #: NP_055140.1
• NCBI GenBank Nucleotide #: NM_014325.3
• UniProt Accession #: Q9ULV4; Q9NSK5; A7MAP0; A7MAP1; B3KU12
• Molecular Weight: 58,947 Da
• NCBI Official Full Name: coronin-1C isoform b
• NCBI Official Synonym Full Names: coronin 1C
• NCBI Official Symbol: CORO1C
• NCBI Official Synonym Symbols: HCRNN4
• NCBI Protein Information: coronin-1C
• UniProt Protein Name: Coronin-1C
• Protein Family: Coronin
• UniProt Gene Name: CORO1C
• UniProt Synonym Gene Names: CRN2; CRNN4

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

Uniprot Description

May be involved in cytokinesis, motility, and signal transduction.