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Immunohistochemistry (IHC) (Anti-CNN1 / Calponin antibody IHC of human myometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Mouse anti-Human CNN1 / Calponin Monoclonal Antibody | anti-CNN1 antibody

Mouse Monoclonal [clone 2F5-1H4] (IgG1,k) to Human CNN1 / Calponin

Gene Names
CNN1; SMCC; Sm-Calp; HEL-S-14
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Protein A Purified
Synonyms
CNN1 / Calponin; Monoclonal Antibody; Mouse Monoclonal [clone 2F5-1H4] (IgG1; k) to Human CNN1 / Calponin; Anti-CNN1 / Calponin Antibody (clone 2F5-1H4) IHC-plus; CNN1; Basic calponin; Calponin; Calponin-1; Calponins; basic; Calponin H1; smooth muscle; SMCC; Sm-Calp; Human CNN1; anti-CNN1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2F5-1H4
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.2
Concentration
1 mg/ml (varies by lot)
Sequence Length
297
Applicable Applications for anti-CNN1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB
Target Species
Human
Immunogen Description
CNN1 (AAH22015, 1 a.a. ~ 298 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
CNN1 / Calponin antibody was raised against cNN1 (AAH22015, 1 a.a. ~ 298 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-CNN1 / Calponin antibody IHC of human myometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-CNN1 / Calponin antibody IHC of human myometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CNN1 / Calponin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-CNN1 / Calponin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,055 Da
NCBI Official Full Name
calponin-1
NCBI Official Synonym Full Names
calponin 1, basic, smooth muscle
NCBI Official Symbol
CNN1
NCBI Official Synonym Symbols
SMCC; Sm-Calp; HEL-S-14
NCBI Protein Information
calponin-1; basic calponin; calponins, basic; calponin H1, smooth muscle; epididymis secretory protein Li 14
UniProt Protein Name
Calponin-1
Protein Family
UniProt Gene Name
CNN1
UniProt Entry Name
CNN1_HUMAN

Uniprot Description

calponin 1: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family.

Protein type: Myosin-binding; Contractile; Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 19p13.2-p13.1

Cellular Component: cytoskeleton; focal adhesion

Molecular Function: calmodulin binding; actin binding

Biological Process: regulation of smooth muscle contraction; actomyosin structure organization and biogenesis

Research Articles on CNN1

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Product Notes

The CNN1 cnn1 (Catalog #AAA245629) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 2F5-1H4] (IgG1,k) to Human CNN1 / Calponin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNN1 / Calponin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB. Researchers should empirically determine the suitability of the CNN1 cnn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNN1 / Calponin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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