Mouse anti-Human CHRNA3 Monoclonal Antibody | anti-CHRNA3 antibody
Mouse Monoclonal Antibody to CHRNA3
WB 1/500-1/1000
FC/FACS 1/200-1/400
ICC 1/50-200
IHC-P 1/50-200
NCBI and Uniprot Product Information
NCBI Description
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
Uniprot Description
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Research Articles on CHRNA3
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Product Notes
The CHRNA3 chrna3 (Catalog #AAA8528713) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal Antibody to CHRNA3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CHRNA3 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemsitry-Paraffin (IHC-P). ELISA 1/10000 WB 1/500-1/1000 FC/FACS 1/200-1/400 ICC 1/50-200 IHC-P 1/50-200. Researchers should empirically determine the suitability of the CHRNA3 chrna3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHRNA3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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